The Rozovsky Lab Primer to Redox Biology
New to redox biology? Here are the Rozovsky group’s members suggestions or the most helpful papers to read.
Those disulfide bonds!
A helpful review by my colleagues Colin Thorpe and Debbie Fass
Chemistry and Enzymology of Disulfide Cross-Linking in Proteins
Thiols and Redox Biology
Jensen, Kristine Steen, Rosa E. Hansen, and Jakob R. Winther. “Kinetic and thermodynamic aspects of cellular
Selenoproteins, selenium and sulfur chemistry
This review article describes all 25 human selenoproteins and their possible biological functions.
2. Labunskyy, V. M.; Hatfield, D. L.; Gladyshev, V. N. Selenoproteins: molecular pathways and physiological roles. Physiol. Rev. 2014, 94, 739-777.
A review that goes
3. Arnér, Elias SJ. “Selenoproteins – What unique properties can arise with selenocysteine in place of cysteine?.” Experimental cell research 316.8 (2010): 1296-1303.
This review lists the differences between Sec and Cys and explains why Sec is more reactive.
4. Liu, Jun, and Sharon Rozovsky. “Membrane-bound selenoproteins.” Antioxidants & redox signaling 23.10 (2015): 795-813.
This review by our group focuses on membrane-bound selenoproteins, including SELENOK and
6. Reich, H. J.;
easy to read and very thorough review of sulfur and selenium properties
A primer about the ER-associated degradation pathway (ERAD): p97,
derlin and SELENOS
1. p97 activity – a review by Bondar and Rapoport 2017
Toward an understanding of the Cdc48/p97 ATPase F1000Res. 2017 Aug 3;6:1318.
2. A primer on the ubiquitin-proteasome by Raymond Deshaies.
3. The structural basis of
Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discovery (2017) 3, 17045
The crystal structure of