New Artwork

Thanks to the fabulous Samantha Santana for our new group portrait! We love this new header image (and the way you captured our personalities)!!

Enantioselective Alkynylation of Unstabilized Cyclic Iminium Ions

Weiye Guan, Samantha Santana, Jennie Liao, and Kelci Henninger have developed a highly enantioselective, copper-catalyzed alkynylation of unstabilized cyclic iminium ions (link). This reaction delivers alpha-chiral amine heterocyclic with easily deprotected nitrogen protecting groups. The key was squeezing the chiral pocket by adding ethyl groups to the PyBox ligand. Congratulations to the team for this great method!

Also unveiling Sam’s awesome artwork celebrating Weiye’s discoveries and PhD!