Alkyl–Alkyl Cross-Coupling Highlighted in OPRD

Group members Shane Plunkett, Corey Basch, and Samantha Santana have developed a Negishi alkylation of alkylpyridinium salts. This is the first example of alkyl–alkyl cross-coupling of alkylpyridinium salts with unactivated alkyl groups. Read it all in their J. Am. Chem. Soc. paper (link). This work was highlighted in Org. Process Res. Dev. Congratulations to this team for a great new reaction!