Thanks to the fabulous Samantha Santana for our new group portrait! We love this new header image (and the way you captured our personalities)!!
Monthly Archives: January 2021
Our Perspective on Stereospecific Cross-Couplings
Jianyu Xu, Olivia Bercher, and Mike Talley collaborated to provide our perspective on nickel-catalyzed, stereospecific C–C and C–B cross-couplings using substrates derived from amines and alcohols (link). Great job, Jianyu, Olivia, and Mike!
Enantioselective Alkynylation of Unstabilized Cyclic Iminium Ions
Weiye Guan, Samantha Santana, Jennie Liao, and Kelci Henninger have developed a highly enantioselective, copper-catalyzed alkynylation of unstabilized cyclic iminium ions (link). This reaction delivers alpha-chiral amine heterocyclic with easily deprotected nitrogen protecting groups. The key was squeezing the chiral pocket by adding ethyl groups to the PyBox ligand. Congratulations to the team for this great method!
Also unveiling Sam’s awesome artwork celebrating Weiye’s discoveries and PhD!