Publication

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Representative Publications

Shi, Y., Zhang, T., Guo, R., Zhang, Z., McCahill, A. L., Tang, Y., … & Pochan, D. J. (2024). Ordered assemblies of peptide nanoparticles with only positive charge. Nature Communications, 15(1), 10057. doi.org/10.1038/s41467-024-54340-9

Zhang, T., Yang, D. B., Kloxin, C. J., Pochan, D. J., & Saven, J. G. (2024). Coarse-Grain Model of Ultrarigid Polymer Rods Comprising Bifunctionally Linked Peptide Bundlemers. Biomacromolecules. doi.org/10.1021/acs.biomac.4c01192

Zhang, Z., Blum, J. E., Guo, R., Kloxin, C. J., Saven, J. G., & Pochan, D. J. (2024). Liquid Crystal Behavior of Uniform Short Rods Made from Computationally Designed Parallel Coiled Coil Building Blocks. ACS Macro Letters, 13, 1591-1597. doi.org/10.1021/acsmacrolett.4c00591

McCahill, A. L., Zhang, T., Saven, J. G., Kloxin, C. J., & Pochan, D. J. (2024). Peptide bundlemer networks or lattices: controlling cross-linking and self-assembly using protein-like display of chemistry. ACS nano, 18(37), 25695-25707. doi.org/10.1021/acsnano.4c07961

Patkar, S. S., Tang, Y., Bisram, A. M., Zhang, T., Saven, J. G., Pochan, D. J., & Kiick, K. L. (2023). Genetic Fusion of Thermoresponsive Polypeptides with UCST‐type Behavior Mediates 1D Assembly of Coiled‐Coil Bundlemers. Angewandte Chemie, e202301331. doi.org/10.1002/ange.202301331

DeFrates, K. G., Engström, J., Sarma, N. A., Umar, A., Shin, J., Cheng, J., … & Messersmith, P. (2022). The Influence of molecular design on structure-property relationships of a supramolecular polymer prodrug. Proceedings of the National Academy of Sciences, 119(44), e2208593119. doi.org/10.1073/pnas.2208593119

Xue, L., Gong, N., Shepherd, S. J., Xiong, X., Liao, X., Han, X., … & Mitchell, M. J. (2022). Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment. Journal of the American Chemical Society, 144(22), 9926-9937 doi.org/10.1021/jacs.2c02706

Guo, R., Sinha, N. J., Misra, R., Tang, Y., Langenstein, M., Kim, K., … & Saven, J. G. (2022). Computational Design of Homotetrameric Peptide Bundle Variants Spanning a Wide Range of Charge States. Biomacromolecules, 23(4), 1652-1661. doi.org/10.1021/acs.biomac.1c01539

Sinha, N. J., Guo, R., Misra, R., Fagan, J., Faraone, A., Kloxin, C. J., … & Pochan, D. J. (2022). Colloid-like solution behavior of computationally designed coiled coil bundlemers. Journal of Colloid and Interface Science, 606, 1974-1982. doi.org/10.1016/j.jcis.2021.09.184

Sinha, N. J., Langenstein, M. G., Pochan, D. J., Kloxin, C. J., & Saven, J. G. (2021). Peptide Design and Self-assembly into Targeted Nanostructure and Functional Materials. Chemical Reviews, 121(22), 13915-13935. doi.org/10.1021/acs.chemrev.1c00712

Kim, K., Kloxin, C. J., Saven, J. G., & Pochan, D. J. (2021). Nanofibers produced by electrospinning of ultrarigid polymer rods made from designed peptide bundlemers. ACS Applied Materials & Interfaces, 13(22), 26339-26351. doi.org/10.1021/acsami.1c04027

Lee, J. Y., Song, Y., Wessels, M. G., Jayaraman, A., Wooley, K. L., & Pochan, D. J. (2020). Hierarchical Self-Assembly of Poly (d-glucose carbonate) Amphiphilic Block Copolymers in Mixed Solvents. Macromolecules, 53(19), 8581-8591. doi.org/10.1021/acs.macromol.0c01575

Wu, D., Sinha, N., Lee, J., Sutherland, B. P., Halaszynski, N. I., Tian, Y., … & Pochan, D. J. (2019). Polymers with controlled assembly and rigidity made with click-functional peptide bundles. Nature, 574(7780), 658-662. doi.org/10.1038/s41586-019-1683-4

Tian, Y., Polzer, F. B., Zhang, H. V., Kiick, K. L., Saven, J. G., & Pochan, D. J. (2018). Nanotubes, plates, and needles: pathway-dependent self-assembly of computationally designed peptides.  Biomacromolecules, 19(11), 4286-4298.

Worthington, P., Drake, K. M., Li, Z., Napper, A. D., Pochan, D. J., & Langhans, S. A. (2017). Beta-hairpin hydrogels as scaffolds for high-throughput drug discovery in three-dimensional cell culture. Analytical biochemistry, 535, 25-34.

Worthington, P., Langhans, S., & Pochan, D. (2017). β-Hairpin peptide hydrogels for package delivery. Advanced drug delivery reviews, 110, 127-136.

Zhang, H. V., Polzer, F., Haider, M. J., Tian, Y., Villegas, J. A., Kiick, K. L., … & Saven, J. G. (2016). Computationally designed peptides for self-assembly of nanostructured lattices. Science Advances, 2(9), e1600307.

Lindsey, S., Piatt, J. H., Worthington, P., Sönmez, C., Satheye, S., Schneider, J. P., … & Langhans, S. A. (2015). Beta hairpin peptide hydrogels as an injectable solid vehicle for neurotrophic growth factor delivery. Biomacromolecules, 16(9), 2672-2683.

Betthausen, E., Hanske, C., Müller, M., Fery, A., Schacher, F. H., Müller, A. H., & Pochan, D. J. (2014). Self-assembly of amphiphilic triblock terpolymers mediated by multifunctional organic acids: Vesicles, toroids, and (undulated) ribbons. Macromolecules, 47(5), 1672-1683.

Jiang, T., Xu, C., Liu, Y., Liu, Z., Wall, J. S., Zuo, X., … & Conticello, V. P. (2014). Structurally defined nanoscale sheets from self-assembly of collagen-mimetic peptides. Journal of the American Chemical Society, 136(11), 4300-4308.

Zhu, J., Zhang, S., Zhang, K., Wang, X., Mays, J. W., Wooley, K. L., & Pochan, D. J. (2013). Disk-cylinder and disk-sphere nanoparticles via a block copolymer blend solution construction. Nature Communications, 4(1), 1-7.

Zhang, S., Zou, J., Zhang, F., Elsabahy, M., Felder, S. E., Zhu, J., … & Wooley, K. L. (2012). Rapid and versatile construction of diverse and functional nanostructures derived from a polyphosphoester-based biomimetic block copolymer system. Journal of the American Chemical Society, 134(44), 18467-18474.

Altunbas, A., Lee, S. J., Rajasekaran, S. A., Schneider, J. P., & Pochan, D. J. (2011). Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles. Biomaterials, 32(25), 5906-5914.

Hayward, R. C., & Pochan, D. J. (2010). Tailored assemblies of block copolymers in solution: it is all about the process. Macromolecules, 43(8), 3577-3584.

Yan, C., & Pochan, D. J. (2010). Rheological properties of peptide-based hydrogels for biomedical and other applications. Chemical Society Reviews, 39(9), 3528-3540.

Cui, H., Chen, Z., Zhong, S., Wooley, K. L., & Pochan, D. J. (2007). Block copolymer assembly via kinetic control. Science, 317(5838), 647-650.

Baker, C., Pradhan, A., Pakstis, L., Pochan, D. J., & Shah, S. I. (2005). Synthesis and antibacterial properties of silver nanoparticles. Journal of nanoscience and nanotechnology, 5(2), 244-249.

Bellomo, E. G., Wyrsta, M. D., Pakstis, L., Pochan, D. J., & Deming, T. J. (2004). Stimuli-responsive polypeptide vesicles by conformation-specific assembly. Nature materials, 3(4), 244-248.

Pochan, D. J., Chen, Z., Cui, H., Hales, K., Qi, K., & Wooley, K. L. (2004). Toroidal triblock copolymer assemblies. Science, 306(5693), 94-97.

Pochan, D. J., Schneider, J. P., Kretsinger, J., Ozbas, B., Rajagopal, K., & Haines, L. (2003). Thermally reversible hydrogels via intramolecular folding and consequent self-assembly of a de novo designed peptide. Journal of the American Chemical Society, 125(39), 11802-11803.

Nowak, A. P., Breedveld, V., Pakstis, L., Ozbas, B., Pine, D. J., Pochan, D., & Deming, T. J. (2002). Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles. Nature, 417(6887), 424-428.