Recent Publications

Stock JM, Shenouda N, Chouramanis NV, Patik JC, Martens CR, Farquhar WB, Chirinos JA, Edwards DG. Effect of acute handgrip and aerobic exercise on wasted pressure effort and arterial wave reflections in healthy aging. Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H617-H628. doi: 10.1152/ajpheart.00133.2023. Epub 2023 Jul 21. PubMed PMID: 37477688.

Tinney EM, Loui P, Raine LB, Hiscox LV, Delgorio PL, Kramer MK, Schwarb H, Martens CR, Kramer AF, Hillman CH, Johnson CL. Influence of mild cognitive impairment and body mass index on white matter integrity assessed by diffusion tensor imaging. Psychophysiology. 2023 Sep;60(9):e14306. doi: 10.1111/psyp.14306. Epub 2023 Apr 10. PubMed PMID: 37038273; NIHMSID:NIHMS1892816.

Sanjana F, Delgorio PL, DeConne TM, Hiscox LV, Pohlig RT, Johnson CL, Martens CR. Vascular determinants of hippocampal viscoelastic properties in healthy adults across the lifespan. J Cereb Blood Flow Metab. 2023 Jul 3;:271678X231186571. doi: 10.1177/0271678X231186571. [Epub ahead of print] PubMed PMID: 37395479.

Fleenor BS, Carlini NA, Martens CR. Nutraceuticals in the Prevention and Therapeutic Treatment of Cardiovascular and Cerebrovascular Disease. J Cardiopulm Rehabil Prev. 2023 May 1;43(3):162-169. doi: 10.1097/HCR.0000000000000773. Epub 2023 Jan 19. Review. PubMed PMID: 36656154.

Freeberg KA, Udovich CAC, Martens CR, Seals DR, Craighead DH. Dietary supplementation with NAD +-boosting compounds in humans: Current knowledge and future directions. J Gerontol A Biol Sci Med Sci. 2023 Apr 17;. doi: 10.1093/gerona/glad106. [Epub ahead of print] PubMed PMID: 37068054.

Delgorio PL, Hiscox LV, McIlvain G, Kramer MK, Diano AM, Twohy KE, Merritt AA, McGarry MDJ, Schwarb H, Daugherty AM, Ellison JM, Lanzi AM, Cohen ML, Martens CR, Johnson CL. Hippocampal subfield viscoelasticity in amnestic mild cognitive impairment evaluated with MR elastography. Neuroimage Clin. 2023;37:103327. doi: 10.1016/j.nicl.2023.103327. Epub 2023 Jan 18. PubMed PMID: 36682312; PubMed Central PMCID: PMC9871742.

Vreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR. Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin. Aging Cell. 2023 Jan;22(1):e13754. doi: 10.1111/acel.13754. Epub 2022 Dec 14. PubMed PMID: 36515353; PubMed Central PMCID: PMC9835564.

Delgorio PL, Hiscox LV, Daugherty AM, Sanjana F, McIlvain G, Pohlig RT, McGarry MDJ, Martens CR, Schwarb H, Johnson CL. Structure-Function Dissociations of Human Hippocampal Subfield Stiffness and Memory Performance. J Neurosci. 2022 Oct 19;42(42):7957-7968. doi: 10.1523/JNEUROSCI.0592-22.2022. Epub 2022 Sep 6. PubMed PMID: 36261271; PubMed Central PMCID: PMC9617610.

Freeberg KA, Craighead DH, Martens CR, You Z, Chonchol M, Seals DR. Nicotinamide Riboside Supplementation for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Midlife and Older Adults. Front Cardiovasc Med. 2022;9:881703. doi: 10.3389/fcvm.2022.881703. eCollection 2022. PubMed PMID: 35620522; PubMed Central PMCID: PMC9127073.

Martens PhD CR, Cohen PhD ML, Lanzi PhD AM, Johnson PhD CL. Expanding Alzheimer’s Research at the University of Delaware and Beyond:: Proposed Delaware Center for Cognitive Aging Research (DECCAR). Dela J Public Health. 2021 Sep;7(4):24-30. doi: 10.32481/djph.2021.09.006. eCollection 2021 Sep. PubMed PMID: 34604765; PubMed Central PMCID: PMC8482989.

Migdal KU, Robinson AT, Watso JC, Babcock MC, Lennon SL, Martens CR, Serrador JM, Farquhar WB. Ten days of high dietary sodium does not impair cerebral blood flow regulation in healthy adults. Auton Neurosci. 2021 Sep;234:102826. doi: 10.1016/j.autneu.2021.102826. Epub 2021 May 27. PubMed PMID: 34058717; PubMed Central PMCID: PMC8315190.

Sanjana F, Delgorio PL, Hiscox LV, DeConne TM, Hobson JC, Cohen ML, Johnson CL, Martens CR. Blood lipid markers are associated with hippocampal viscoelastic properties and memory in humans. J Cereb Blood Flow Metab. 2021 Jun;41(6):1417-1427. doi: 10.1177/0271678X20968032. Epub 2020 Oct 26. PubMed PMID: 33103936; PubMed Central PMCID: PMC8142125.

Delgorio PL, Hiscox LV, Daugherty AM, Sanjana F, Pohlig RT, Ellison JM, Martens CR, Schwarb H, McGarry MDJ, Johnson CL. Effect of Aging on the Viscoelastic Properties of Hippocampal Subfields Assessed with High-Resolution MR Elastography. Cereb Cortex. 2021 May 10;31(6):2799-2811. doi: 10.1093/cercor/bhaa388. PubMed PMID: 33454745; PubMed Central PMCID: PMC8107787.

Migdal KU, Robinson AT, Watso JC, Babcock MC, Lennon SL, Martens CR, Serrador JM, Farquhar WB. A high salt meal does not impair cerebrovascular reactivity in healthy young adults. Physiol Rep. 2020 Oct;8(19):e14585. doi: 10.14814/phy2.14585. PubMed PMID: 33038066; PubMed Central PMCID: PMC7547584.

DeConne TM, Muñoz ER, Sanjana F, Hobson JC, Martens CR. Cardiometabolic risk factors are associated with immune cell mitochondrial respiration in humans. Am J Physiol Heart Circ Physiol. 2020 Aug 1;319(2):H481-H487. doi: 10.1152/ajpheart.00434.2020. Epub 2020 Jul 17. PubMed PMID: 32678706; PubMed Central PMCID: PMC7473919.

Babcock MC, Robinson AT, Migdal KU, Watso JC, Martens CR, Edwards DG, Pescatello LS, Farquhar WB. High Salt Intake Augments Blood Pressure Responses During Submaximal Aerobic Exercise. J Am Heart Assoc. 2020 May 18;9(10):e015633. doi: 10.1161/JAHA.120.015633. Epub 2020 May 14. PubMed PMID: 32406312; PubMed Central PMCID: PMC7660875.

Babcock MC, Robinson AT, Watso JC, Migdal KU, Martens CR, Edwards DG, Pescatello LS, Farquhar WB. Salt Loading Blunts Central and Peripheral Postexercise Hypotension. Med Sci Sports Exerc. 2020 Apr;52(4):935-943. doi: 10.1249/MSS.0000000000002187. PubMed PMID: 31609296; PubMed Central PMCID: PMC7144834.

Martens CR, Rossman MJ, Mazzo MR, Jankowski LR, Nagy EE, Denman BA, Richey JJ, Johnson SA, Ziemba BP, Wang Y, Peterson CM, Chonchol M, Seals DR. Short-term timerestricted feeding is safe and feasible in non-obese healthy midlife and older adults. Geroscience. 2020 Apr;42(2):667-686. doi: 10.1007/s11357-020-00156-6. Epub 2020 Jan 23. PubMed PMID: 31975053; PubMed Central PMCID: PMC7206473.

Johnson LC, Parker K, Aguirre BF, Nemkov TG, D’Alessandro A, Johnson SA, Seals DR, Martens CR. The plasma metabolome as a predictor of biological aging in humans. Geroscience. 2019 Dec;41(6):895-906. doi: 10.1007/s11357-019-00123-w. Epub 2019 Nov 9. PubMed PMID: 31707594; PubMed Central PMCID: PMC6925078.

Rossman MJ, LaRocca TJ, Martens CR, Seals DR. Healthy lifestyle-based approaches for successful vascular aging. J Appl Physiol (1985). 2018 Dec 1;125(6):1888-1900. doi: 10.1152/japplphysiol.00521.2018. Epub 2018 Sep 13. Review. PubMed PMID: 30212305; PubMed Central PMCID: PMC6842891.

Santos-Parker JR, Santos-Parker KS, McQueen MB, Martens CR, Seals DR. Habitual aerobic exercise and circulating proteomic patterns in healthy adults: relation to indicators of healthspan. J Appl Physiol (1985). 2018 Nov 1;125(5):1646-1659. doi: 10.1152/japplphysiol.00458.2018. Epub 2018 Sep 20. PubMed PMID: 30236049; PubMed Central PMCID: PMC6295489.

Johnson LC, Martens CR, Santos-Parker JR, Bassett CJ, Strahler TR, Cruickshank-Quinn C, Reisdorph N, McQueen MB, Seals DR. Amino acid and lipid associated plasma metabolomic patterns are related to healthspan indicators with ageing. Clin Sci (Lond). 2018 Aug 31;132(16):1765-1777. doi: 10.1042/CS20180409. Print 2018 Aug 31. PubMed PMID: 29914938.

Martens CR, Denman BA, Mazzo MR, Armstrong ML, Reisdorph N, McQueen MB, Chonchol M, Seals DR. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults. Nat Commun. 2018 Mar 29;9(1):1286. doi: 10.1038/s41467-018-03421-7. PubMed PMID: 29599478; PubMed Central PMCID: PMC5876407.

LaRocca TJ, Martens CR, Seals DR. Nutrition and other lifestyle influences on arterial aging. Ageing Res Rev. 2017 Oct;39:106-119. doi: 10.1016/j.arr.2016.09.002. Epub 2016 Sep 28. Review. PubMed PMID: 27693830; PubMed Central PMCID: PMC5373983