2019 HPC Symposia

Feb 27, 2019

Title:  Determining the early stages of HIV life-cycle using the computational microscope

Location: Faculty Commons (116 Pearson Hall)

Time: 10 a.m. to noon

Lentiviruses like HIV are characterized by their ability to infect non-dividing cells. Therefore, during the early stages of the viral infection, HIV’s genome must move through the cytoplasm from the cellular membrane all the way to the cell nucleus. In addition, the viral RNA is reverse transcribed into DNA inside of the viral capsid for proper genome integration. Here, we present our computational approach to elucidate, at the molecular level, the host-pathogen interactions that modulate the viral particle trafficking through the cytoplasm. In addition, by employing large-scale computing based on multi-replica simulations, we establish the energetics associated with viral RNA reverse-transcription. Lastly, we introduce a novel multi-scale framework which enables the determination of the atomic structures of capsid assemblies based on cryo electron-tomography. Importantly, our approach relies on current petascale supercomputers to reveal the molecular details of biological events which occur on the second time-scale and span over several micrometers in magnitude – the latter involving systems containing multi-million atoms. 

Presenters:  Chaoyi Xu of Juan Perilla’s Research Group
Other authors: Dipak B. Sanap, and Juan R. Perilla

Jul 24, 2019

Title: Poster Session

Location: 132 Evans Hall, Collaboration Hub (iSuite)

Time: 10 a.m. to noon

IT Research Computing is hosting a poster session showcasing different research across campus that is being done using high performance computing. All research groups are invited to submit posters for projects on any HPC resource locally or nationally, including Mills, Farber, Caviness, XSEDE clusters, department clusters, and clusters at other institutions.

Researchers are welcome to bring an existing poster or create a new poster. New posters can be printed through IT Client Support & Services in Smith Hall. Those who register to present a poster at the symposium will be able to print their poster for free before Friday, June 19. Documentation for poster printing is available at the IT web site.

To sign up to present a poster and/or receive assistance with your poster, please go to the poster signup page to reserve your spot.

All UD researchers are encouraged to attend to learn about other projects going on at the University and to connect with colleagues about high performance computing.

Refreshments will be served.

Oct 9, 2019

Title: Information Technologies

Location: Faculty Commons (116 Pearson Hall)

Time: 10 a.m. to noon

Presenter: IT Research CyberInfrastructure (IT-RCI) Group

HPC SYMPOSIUM-Oct2019 presented by IT-RCI Group

Introduction to Slurm presented by Jeff Frey