Welcome to the Patel Research Group in the Department of Chemistry and Biochemistry at the University of Delaware. Our group uses high-performance computing platforms (conventional CPU-based and next-generation GPU and hybrid CPU-GPU) to address applied and fundamental aspects of a variety of physical, biophysical, and technologically-relevant condensed-phase systems. Broadly, topics of current interest include:
- Machine Learning (Neural Networks, Support Vector Machines, Deep Learning)
- Biophysics of lipid bilayers and model cell membranes
- Design of Peptide-Based Cell-Penetrating Pharmaceuticals
- Protein-Protein interactions
- Protein-ligand binding free energetics and accurate prediction
- Aspects of protein and peptide folding
- Emerging pictures of biophysical processes in crowded cellular environments,
- Aspects of solvation (hydration) at the molecular level and their relation to a broad range of phenomena spanning the aforementioned systems
- Carbon nanomaterials properties and modeling at the atomic and mesoscales
- Development of Molecular Simulation Software for Graphics Processors
- Development and Implementation of associated computational methods.
