Neo 400 MHz

Bruker AV400 NMR Spectrometer with a CryoProbe

The Neo 400 MHz NMR spectrometer is equipped with the latest generation Bruker Avance Neo console and a cryogenic QNP (1H, 13C, 19F, and 31P) probe for maximum sensitivity and flexibility.  The sensitivity of  13C, 19F, and 31P of this cold-probe is 3 to 4 times better than a conventional QNP probe, which allows for rapid turn-around of routine 13C experiments.  The Neo 400 MHz NMR also has a sample changer which accepts sample submission 24/7.  The day-queue is reserved for a quick turn-around analysis for experiments such as 1H, 13C, and 2D COSY.  The night-queue is for  experiments that require one or more hours of instrument time such as 13C NMR for diluted samples and two-dimensional experiments (HMQC, HSQC, NOESY).

Data acquired on the Neo 400 NMR spectrometer is automatically transferred to our NMR data server.  NMR training on instrument automation, sample loading/unloading, data processing, and magnet laboratory safety is available for all researchers at the University of Delaware and required for access to this instrument.

No web-reservation is required for the use of this instrument.

The Neo 400 NMR is an NSF CRIF funded spectrometer and it is Cyber-enabled for remote control and access.  Academic users of nearby colleges and high schools are welcome to use this spectrometer.  Please contact NMR facilities manager for details.

Funding information:

(1)    Acquisition of 400 MHz NMR Spectrometer”, NSF MIR 0421224 (Principal Investigator: Joseph Fox, Co-principal Investigators: John Koh, Tatyana Polenova, and Charles Riordan) 2005 – 2008.

(2)   Purchase of Cryoprobe for Cryo-enabled NMR Spectroscopy”, NSF CRIF MU CHE0840401 (Principal Investigator: Klaus Theopold, Co-principal Investigators: Joseph Fox and Shi Bai) 2009 – 2012.

(3)  “Discovery of Chemical Probes and Therapeutic Leads”, COBRE P.I. Fox, J. M. P20GM104316