The Neo 400 MHz NMR spectrometer is equipped with the latest generation Bruker Avance Neo console and a cryogenic QNP (1H, 13C, 19F, and 31P) probe for maximum sensitivity and flexibility. The sensitivity of 13C, 19F, and 31P of this cold-probe is 3 to 4 times better than a conventional QNP probe, which allows for rapid turn-around of routine 13C experiments. The Neo 400 MHz NMR also has a sample changer which accepts sample submission 24/7. The day-queue is reserved for a quick turn-around analysis for experiments such as 1H, 13C, and 2D COSY. The night-queue is for experiments that require one or more hours of instrument time such as 13C NMR for diluted samples and two-dimensional experiments (HMQC, HSQC, NOESY).
Data acquired on the Neo 400 NMR spectrometer is automatically transferred to our NMR data server. NMR training on instrument automation, sample loading/unloading, data processing, and magnet laboratory safety is available for all researchers at the University of Delaware and required for access to this instrument.
No web-reservation is required for the use of this instrument.
The Neo 400 NMR is an NSF CRIF funded spectrometer and it is Cyber-enabled for remote control and access. Academic users of nearby colleges and high schools are welcome to use this spectrometer. Please contact NMR facilities manager for details.
(1) Acquisition of 400 MHz NMR Spectrometer”, NSF MIR 0421224 (Principal Investigator: Joseph Fox, Co-principal Investigators: John Koh, Tatyana Polenova, and Charles Riordan) 2005 – 2008.
(2) Purchase of Cryoprobe for Cryo-enabled NMR Spectroscopy”, NSF CRIF MU CHE0840401 (Principal Investigator: Klaus Theopold, Co-principal Investigators: Joseph Fox and Shi Bai) 2009 – 2012.
(3) “Discovery of Chemical Probes and Therapeutic Leads”, COBRE P.I. Fox, J. M. P20GM104316