Publications
Publications
JOURNAL PUBLICATIONS
1. Lv M, Zhou Y, Polson SW, Wan LQ, Wang M, Han L, Wang L, Lu XL. Identification of Chondrocyte Genes and Signaling Pathways in Response to Acute Joint Inflammation. Sci Rep. 2019 Jan 14;9(1):93. doi: 10.1038/s41598-018-36500-2. PubMed PMID: 30643177; PubMed Central PMCID: PMC6331554.
2. Zhou Y, Lv M, Li T, Zhang T, Duncan R, Wang L, Lu XL. Spontaneous calcium signaling of cartilage cells: from spatiotemporal features to biophysical modeling. FASEB J. 2019 Jan 2:fj201801460R. doi: 10.1096/fj.201801460R. [Epub ahead of print] PubMed PMID: 30601690
3. Zhao W, Li T, Li Y, O’Brien DJ, Terrones M, Wei B, Suhr J, Lu XL. Mechanical properties of nanocomposites reinforced by carbon nanotube sponges. Journal of Materiomics. 2018; 4: 157-164
4. Fleck AKM, Kruger U, Carlson K, Waltz C, McCallum SA, Lucas Lu X, Wan LQ. Zonal variation of MRI-measurable parameters classifies cartilage degradation. J Biomech. 2017; 65:176-184. PMID: 29126604.
5. Zhang J, Liao L, Zhu J, Wan X, Xie M, Zhang H, Zhang M, Lu L, Yang H, Jing D, Liu X, Yu S, Lu XL, Chen C, Shan Z, Wang M. Osteochondral Interface Stiffening in Mandibular Condylar Osteoarthritis. Journal of Dental Research. 2017; 22034517748562. PubMed [journal] PMID: 29298566
6. Lv M, Zhou Y, Chen X, Han L, Wang L, Lu XL. Calcium Signaling of in situ Chondrocytes in Articular Cartilage under Compressive Loading: Roles of Calcium Sources and Cell Membrane Ion Channels. J Orthop Res. 2018; 36(2):730-738. PMID: 28980722
7. Chandrasekaran P, Doyran B, Li Q, Han B, Bechtold TE, Koyama E, Lu XL, Han L. Biomechanical properties of murine TMJ articular disc and condyle cartilage via AFM-nanoindentation. J Biomech. 2017; 60:134-141. PubMed PMID: 28688538
8. Zhang H, Cui JW, Lu XL, Wang MQ. Finite element analysis on tooth and periodontal stress under simulated occlusal loads. Journal of oral rehabilitation. 2017; 44(7):526-536. PubMed [journal] PMID: 28370179
9. Doyran B, Tong W, Li Q, Jia H, Zhang X, Chen C, Enomoto-Iwamoto M, Lu XL, Qin L, Han L. Nanoindentation Modulus of Murine Cartilage: A Sensitive Indicator of the Initiation and Progression of Post-Traumatic Osteoarthritis, Osteoarthritis and Cartialge, 2017; 25(1): 109-117. PMID: 27568574
10. Jia H, Ma X, Tong W, Doyran B, Sun Z, Wang L, Zhang X, Zhou Y, Badar F, Chandra A, Lu XL, Xia Y, Han L, Enomoto-Iwamoto M, Qin L. EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation. Proceedings of the National Academy of Sciences USA, 2016; 113(50):14360-14365. PMID: 27911782
11. Fan L, Pei S, Lu XL, Wang L. A multiscale 3D finite element analysis of fluid/solute transport in mechanically loaded bone, Bone Research, 2016; 4, 16032; PMID: 27722020
12. Abu-Hakmeh A, Kung A, Mintz B, Kamal S, Cooper J, Lu XL, Wan LQ. Sequential Gelation of Tyramine Substituted Hyaluronic Acid Hydrogels Enhances Mechanical Integrity and Cell Viability, Medical & Biological Engineering & Computing, 2016; 54(12):1893-1902. PMID: 27056409
13. Han B, Chery DC, Yin J, Lu XL, Lee D, Han L. Impacts of pH and Ionic Strength on the Nanomechanical Properties of Ionically Cross-linked Polyelectrolyte Networks, Soft Matter. Soft Matter, 2016; 12: 1158-1169. PMID: 26599600
14. Zhao W, Elias AL, Rajukumar LP, Kim HI, O’Brien DJ, Zimmerman BK, Penev ES, Terrones M, Yakobson BI, Wei B, Lu XL, Suhr J. Controllable and Predictable Viscoelastic Behavior of 3D Boron-doped Multiwalled Carbon Nanotube Sponges. Particle & Particle Systems Characterization, 2016; 33(1): 21-26. DOI: 10.1002/ppsc.201500136. (Cover Story)
15. Zhao W, Shan C, Elias AL, Rajukumar LP, O’Brien DJ, Terrones M, Wei B, Suhr J, Lu XL. Hyperelasticity of Three-Dimensional Carbon Nanotube Sponge Controlled by the Stiffness of Covalent Junctions. Carbon. 95: 640-645. 2015. doi: 10.1016/j.carbon.2015.08.068
16. Moore AC, Zimmerman BK, Chen X, Lu XL, Burris DL. Experimental characterization of biphasic materials using rate-controlled Hertzian indentation. Tribology international. 2015; 89:2-8. PMID: 26160994
17. Chen X, Zhou Y, Wang L, Santare MH, Wan LQ, Lu XL. Determining Tension-Compression Nonlinear Mechanical Properties of Articular Cartilage from Indentation Testing. Annals of biomedical engineering. 2015; 44(4), 1148-1158. PMID: 26240062
18. Zhou Y, David MA, Chen X, Wan LQ, Duncan RL, Wang L, Lu XL. Effects of Osmolarity on the Spontaneous Calcium Signaling of In Situ Juvenile and Adult Articular Chondrocytes. Annals of biomedical engineering. 2015; 44(4), 1138-1147. PMID: 26219403
19. Parajuli A, Liu C, Li W, Gu X, Lai X, Pei S, Price C, You L, Lu XL, Wang L. Bone’s responses to mechanical loading are impaired in type 1 diabetes. Bone. 2015; 81:152-160. PMID: 26183251
20. Li Q, Doyran B, Gamer LW, Lu XL, Qin L, Ortiz C, Grodzinsky AJ, Rosen V, Han L. Biomechanical properties of murine meniscus surface via AFM-based nanoindentation. Journal of biomechanics. 2015; 48(8):1364-70. PMID: 25817332
21. Ruggiero L, Zimmerman BK, Park M, Han L, Wang L, Burris DL, Lu XL. Roles of the Fibrous Superficial Zone in the Mechanical Behavior of TMJ Condylar Cartilage. Annals of biomedical engineering. 2015; PMID: 25893511
22. Zhou Y, Park M, Cheung E, Wang L, Lu XL. The effect of chemically defined medium on spontaneous calcium signaling of in situ chondrocytes during long-term culture. Journal of biomechanics. 2015; 48(6):990-6. PMCID: PMC4380595
23. Singh AV, Raymond M, Pace F, Certo A, Zuidema JM, McKay CA, Gilbert RJ, Lu XL, Wan LQ. Astrocytes increase ATP exocytosis mediated calcium signaling in response to microgroove structures. Scientific reports. 2015; 5:7847. PMCID: PMC4297955
24. Chen X, Zimmerman BK, Lu XL. Determine the equilibrium mechanical properties of articular cartilage from the short-term indentation response. Journal of biomechanics. 2015; 48(1):176-80. PMID: 25528721
25. Zimmerman BK, Bonnevie ED, Park M, Zhou Y, Wang L, Burris DL, Lu XL. Role of interstitial fluid pressurization in TMJ lubrication. Journal of dental research. 2015; 94(1):85-92. PMID: 25297115
26. Lai X, Price C, Lu XL, Wang L. Imaging and quantifying solute transport across periosteum: implications for muscle-bone crosstalk. Bone. 2014; 66:82-9. PMID: 24928492
27. Qiu J, Baik AD, Lu XL, Hillman EM, Zhuang Z, Dong C, Guo XE. A noninvasive approach to determine viscoelastic properties of an individual adherent cell under fluid flow. Journal of biomechanics. 2014; 47(6):1537-41. PMID: 24581798
28. Jing D, Baik AD, Lu XL, Zhou B, Lai X, Wang L, Luo E, Guo XE. In situ intracellular calcium oscillations in osteocytes in intact mouse long bones under dynamic mechanical loading. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2014; 28(4):1582-92. PMID: 24347610
29. Zhou B, Liu XS, Wang J, Lu XL, Fields AJ, Guo XE. Dependence of mechanical properties of trabecular bone on plate-rod microstructure determined by individual trabecula segmentation (ITS). Journal of biomechanics. 2014; 47(3):702-8. NIHMSID: NIHMS552011 PubMed [journal] PMID: 24360196, PMCID: PMC3925244
30. Jing D, Lu XL, Luo E, Sajda P, Leong PL, Guo XE. Spatiotemporal properties of intracellular calcium signaling in osteocytic and osteoblastic cell networks under fluid flow. Bone. 2013; 53(2):531-40. PMID: 23328496
31. Shan C, Zhao W, Lu XL, O’Brien DJ, Li Y, Cao Z, Elias AL, Cruz-Silva R, Terrones M, Wei B, Suhr J. Three-dimensional nitrogen-doped multiwall carbon nanotube sponges with tunable properties. Nano letters. 2013; 13(11):5514-20. PMID: 24134742
32. Lu XL, Huo B, Park M, Guo XE. Calcium response in osteocytic networks under steady and oscillatory fluid flow. Bone. 2012; 51(3):466-73. PMID: 22750013
33. Lu XL, Huo B, Chiang V, Guo XE. Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research. 2012; 27(3):563-74. PMID: 22113822
34. Su JH, Xu F, Lu XL, Lu TJ. Fluid flow induced calcium response in osteoblasts: mathematical modeling. Journal of biomechanics. 2011; 44(11):2040-6. PMID: 21665208
35. Qiu J, Baik AD, Lu XL, Hillman EM, Zhuang Z, Guo XE. Theoretical Analysis of Novel Quasi-3D Microscopy of Cell Deformation. Cellular and molecular bioengineering. 2011; 5(2):165-172. PMID: 22707985
36. Baik AD, Lu XL, Qiu J, Huo B, Hillman EM, Dong C, Guo XE. Quasi-3D cytoskeletal dynamics of osteocytes under fluid flow. Biophysical journal. 2010; 99(9):2812-20. PMID: 21044578
37. Wan LQ, Kang SM, Eng G, Grayson WL, Lu XL, Huo B, Gimble J, Guo XE, Mow VC, Vunjak-Novakovic G. Geometric control of human stem cell morphology and differentiation. Integrative biology: quantitative biosciences from nano to macro. 2010; 2(7-8):346-53. PMID: 20652175
38. Maleke C, Luo J, Gamarnik V, Lu XL, Konofagou EE. Simulation study of amplitude-modulated (AM) harmonic motion imaging (HMI) for stiffness contrast quantification with experimental validation. Ultrasonic imaging. 2010; 32(3):154-76. PMID: 20718245
39. Lu XL, Wan LQ, Guo XE, Mow VC. A linearized formulation of triphasic mixture theory for articular cartilage, and its application to indentation analysis. Journal of biomechanics. 2010; 43(4):673-9. PMID: 19896670
40. Yadav VK, Balaji S, Suresh PS, Liu XS, Lu X, Li Z, Guo XE, Mann JJ, Balapure AK, Gershon MD, Medhamurthy R, Vidal M, Karsenty G, Ducy P. Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nature medicine. 2010; 16(3):308-12. PMID: 20139991
41. Huo B, Lu XL, Costa KD, Xu Q, Guo XE. An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation. Cell calcium. 2010; 47(3):234-41. PMID: 20060586
42. Huo B, Lu XL, Guo XE. Intercellular calcium wave propagation in linear and circuit-like bone cell networks. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences. 2010; 368(1912):617-33. PMID: 20047942
43. Mow VC, Michael Lai W, Setton LA, Gu W, Yao H, Wan LQ, Lu XL. Discussion: “On the Thermodynamical Admissibility of the Triphasic Theory of Charged Hydrated Tissues” (Huyghe, J. M., Wilson, W., and Malakpoor, K., ASME J. Biomech. Eng., 2009, 131, p. 044504). Journal of biomechanical engineering. 2009; 131(9):095501. PMID: 19725705
44. Chan ME, Lu XL, Huo B, Baik AD, Chiang V, Guldberg RE, Lu HH, Guo XE. A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology. Cellular and molecular bioengineering. 2009; 2(3):405-415. PMID: 20827376
45. Lu XL, Mow VC, Guo XE. Proteoglycans and mechanical behavior of condylar cartilage. Journal of dental research. 2009; 88(3):244-8. PMID: 19329458
46. Huo B, Lu XL, Hung CT, Costa KD, Xu Q, Whitesides GM, Guo XE. Fluid Flow Induced Calcium Response in Bone Cell Network. Cellular and molecular bioengineering. 2008; 1(1):58-66. PMID: 20852730
47. Lu XL, Mow VC. Biomechanics of articular cartilage and determination of material properties. Medicine and science in sports and exercise. 2008; 40(2):193-9. PMID: 18202585
48. Lu XL, Miller C, Chen FH, Guo XE, Mow VC. The generalized triphasic correspondence principle for simultaneous determination of the mechanical properties and proteoglycan content of articular cartilage by indentation. Journal of biomechanics. 2007; 40(11):2434-41. PMID: 17222852
49. Lu XL, Sun DD, Guo XE, Chen FH, Lai WM, Mow VC. Indentation determined mechanoelectrochemical properties and fixed charge density of articular cartilage. Annals of biomedical engineering. 2004; 32(3):370-9. PMID: 15095811
BOOK & BOOK CHAPTERS
- Yao, H., Wu, Y., Lu, X.L.
- “Cartilage Mechanobiology”, in Mechanobiology Handbook, edited by Jiro Nagatomi.ISBN: 9781420091212, Taylor & Francis Group LLC, 2010 (work after joining UD)
- Mow, V.C., Lu, X.L., Wan, L.Q.
- “Rigorous Mechanics And Elegant Mathematics Formulation of Constitutive Laws for Complex Materials: An Example from Biomechanics”, in From Waves in Complex Systems to Dynamics of Generalized Continua, ISBN: 9789814340717, World Scientific Publishing Company, 2010.
- Huo, B., Lu, X.L., Guo X.E.
- “Fluid Flow Induced Calcium Response in Bone Cell Network”, in Tributes to Yuan-Cheng Fung on His 90th Birthday: Biomechanics, from Molecules to Man, edited by Shu Chien et al., ISBN: 9789814289870 World Scientific Publishing Company, 2009
- Xin Lu, Tao Zhang
- “Engineering Design Graphics – AutoCAD 2000”, in Chinese, ISBN：9787114034374. China Communications Press, Beijing, China, 2000