Athletic Training Research Laboratory
The primary focus of this lab within the domain of Sports Medicine is to study sensorimotor and neurocognitive aspects of musculoskeletal related injury. In addition, there is a strong emphasis on sport related concussions.
- NCAA/DoD Grand Alliance Concussion Education Research Education (CARE) program
- A Randomized Control Trial Evaluating the Effectiveness of the Get aHEAD Safely in Soccer™ Heading Intervention for Improving Safe Play and Reducing Concussion in Youth Soccer Players
- Long-Term Effects Following an Acute Lateral Ankle Sprain in Collegiate Student-Athletes
- Examination of Purposeful Heading and Neuropsychological Test Performance in Intercollegiate Soccer Players
- Ankle Injury Assessment and Tracking in an Athletic Population
Cardiovascular Nutrition Research Laboratory
Our research focus is on the role of dietary nutrients on the cardiovascular system in healthy and diseased states. Our research uses a variety of techniques to study heart and blood vessel function in humans.
- Vascular Effects of Dietary Potassium in Humans
- Vascular Effects of Dietary Salt in Humans with Salt-Resistant Blood Pressure
- The Effect of Melatonin and Sodium on Vascular Health, Oxidative Stress and Cardiovascular Reactivity
- Vegetarian Diets and Vascular Function
- Habitual Diet Study
- Impact of Diet on the Gut Microbiota
Cardiovascular Physiology Research Laboratory
Our research focuses on examining blood pressure regulation and autonomic nervous system function in humans. We focus on understanding how fluid and electrolyte imbalance in the body affect blood pressure control at rest and during exercise, and brain blood vessel function. We study healthy adults and those who are hypertensive or chronically consume high dietary sodium.
- The influence of Habitual Physical Activity and Cardiorespiratory Fitness on Cardiovascular Responses to Dietary Salt
- Cardiovascular and Cerebrovascular Reactivity to Acute Dietary Sodium
- Blood Pressure Control During Mild Dehydration, and the Effect of Aging
- The Effects of Dietary Salt on Blood Pressure Responses to Acute Aerobic Exercise
Concussion Research Laboratory
The goals of the Concussion Research Group are to explore balance following sports related concussion particularly during recovery and beyond return to participation & to investigate the effect of repetitive head impacts on neurological health and physiology in collision sport athletes.
- NCAA/DoD Grand Alliance Concussion Education Research Education (CARE) program
- Service Academy Longitudinal mTBI Outcomes Study (SALTOS)
- Unresolved Post-Concussion Balance Deficits and Subsequent Musculoskeletal Injury
- Neurobiological Consequences Subconcussive Impacts and Concussion in Ice Hockey
Control of Balance and Locomotion Research Laboratory
Our research focuses on understanding the neural and biomechanical basis of human upright balance. We investigate how the nervous system uses sensory information to estimate body dynamics and guide motor processes for upright balance control. The goal is to better understand patient populations with neurological disease and injury that lead to balance problems.
Website: Control of Balance and Locomotion Research Laboratory
Director: John J. Jeka & Hendrik Reimann
- Mechanisms of Balance Control during Locomotion
- Sub-Concussion and Balance Control
- Sensory Processing and Balance Control during Walking in CP & Parkinson’s Disease
- Balance During Obstacle Avoidance
- Sensor Fusion for Balance Control in Children with Cerebral Palsy
Developmental Motor Control Research Laboratory
Our research focuses on ways to improve the ability of children to move successfully in their everyday lives. We study the development of motor control and coordination as well as perceptual, cognitive, and motor relationships in typically and atypically developing children.
- Patterns of cortical oxygenation as a function of motor planning with different Tower of Hanoi puzzles in children with and without developmental coordination disorder
- A longitudinal study of neural biomarkers of brain plasticity in a biofeedback rehabilitation protocol for stroke patients
Exercise Neuroscience Research Laboratory
The goal of the ExNeuro Lab is to provide new knowledge about the use of exercise to improve mobility and fitness in people with Parkinson’s disease and older adults. We focus on the effects of exercise on the nervous system and the prevention of age- or disease-related slowing.
- Exercise Intervention Research: SpeedGeezer
- PD: Bradykinesia with Segmented Motor Output
- Motor Unit Correlates of Power
Falls and Mobility Research Laboratory
Our research focuses on how to reduce the incidence of falls, lessen the severity of fall injury, and enable physical activity in patient populations. We employ clinical and biomechanical analyses of mobility and balance, including tests of fall recovery. Our research is applicable to many groups of people, including older adults, individuals with chronic stroke, and children with cerebral palsy.
- Fall-recovery training for individuals with chronic stroke
- Development of a comprehensive evaluation of postural control in children with cerebral palsy
- A study of how counter-rotation movements help maintain balance
- The effects of backward walking training on balance, mobility, strength and fall recovery in older adults
Gait Biomechanics Research Laboratory
Our research focuses on mechanisms responsible for changes in gait due to age, pathology, injury, or exercise. We examine the role of muscle function and behavior in gait biomechanics by testing the response of gait to transient, fatigue-induced changes in muscle strength and by studying how long-term physical activity or gait behavior relates to gait biomechanics and joint loading in order to develop targeted interventions to help adults maintain mobility across the lifespan.
- Development of tools for real-world gait analysis
- Determining the role of muscle weakness in altered gait
Molecular Physiology Research Laboratory
The focus of our lab is to understand the molecular mechanisms responsible for physiological and pathological processes. Our lab primarily focuses on skeletal muscle related pathologies and sports related head impact.
- Elucidating the role of EVs in the progression and severity of neuromuscular disorders
- Utilizing EVs from circulation and other biological fluids as biomarkers of disease,, progression of disease, and efficacty of therapeutics and treatments
- Engineering EVs for targeted therapeutic delivery
Motor Neuroscience and Neuroimaging Research Laboratory
Our research focuses on advancing knowledge of human neural control of movement in health and disease to develop rehabilitation interventions for improving motor function. Our research is geared toward a better understanding of the neural mechanisms contributing to motor symptoms in Parkinson’s disease and utilizing integrated functional and structural brain imaging techniques, detailed assessments of motor and non-motor function, and genetic data.
Website: Motor Neuroscience and Neuroimaging Research Laboratory
Director: Roxana G. Burciu
- Motor network deficits in Parkinson’s disease
- Motor phenotypes in Parkinson’s disease
Neuromechanics Research Laboratory
Our lab studies the neurologic and biomechanical aspects of injury proneness. The momentary loss of situational awareness causing neruomusculoskeletal injuries can be studied by measuring how the brain controls protective muscle tone/stiffness. We apply our results to injury prevention and rehabilitation programs to help mitigate future accidents.
- Neuromechanical contributions to hamstring stiffness dysregulation and injury
- Neuromechanical links between cognition, fear, and joint instability
- Factors influencing upper extremity tissue characteristics and injury in youth overhead athletes
Neurovascular Aging Laboratory
Our research focuses on understanding the mechanisms by which impaired vascular function contributes to cognitive impairment and risk of Alzheimer’s disease in older adults. Our goal is to develop novel pharmacological, lifestyle and dietary interventions to delay or reverse age-associated cognitive decline by increasing blood flow to the brain.
- NAD+ therapy for improving memory & cerebrovascular function in patients with MCI
- The impact of vascular aging on brain stiffness and cognitive function
- Mechanisms of impaired brain blood flow with aging
Orthotics & Prosthetics for Enhanced Mobility Laboratory
Our lab focuses on orthotic and prosthetic biomechanics, with goals of understanding the interaction between the human musculoskeletal system and orthotic/prosthetic devices, and optimizing the design and prescription of orthotic and prosthetic devices to enable all orthotic and prosthetic users to reach their optimal functional level.
Website: Orthotics & Prosthetics for Enhanced Mobility Laboratory
Director: Elisa S. Arch
- Objective Clinical Prescription of Passive-Dynamic Ankle-Foot Orthoses to Optimize Patient Outcomes
- Evaluating the Influence of Novel Deformable Foot Orthoses on the Energetics of Walking
- Comparative Effect of Commercially Available Custom Dynamic Orthoses
- Development of an Ankle-Foot Orthosis with Integrated Functional Textiles
- Soft ankle foot orthosis using artificial muscle, DEAFO
Sensorimotor Control & Robotic Rehabilitation Research Laboratory
Our research uses a KINARM robotic exoskeleton to study sensorimotor function and rehabilitation of the upper limb in individuals with stroke and other neurologic diseases/injuries. We focus on the neural and behavioral mechanisms that contribute to learning and recovery of sensory and motor function after neural injury through the use of robotics, neuroimaging, neurostimulation, and computational modeling.
- Relationship of eye movements and proprioception after stroke
- Proprioceptive learning after stroke
- Multi-modal learning after stroke
- Robotics for rehabilitation
Vascular Function in Chronic Disease Research Laboratory
Our research focuses on understanding vascular function and blood flow regulation throughout the lifespan and in the face of chronic disease, with particular emphasis on cardiovascular disease. Our goal is to improve the overall health and quality of life in people through exercise, lifestyle, and pharmacological interventions.
Website: Vascular Function in Chronic Disease Research Laboratory
Director: Melissa Witman
- Vascular Consequences of Duchenne Muscular Dystrophy
- Arterial Stiffness and Vascular Function in Healthy Children
- Sleep and Cardiovascular Health in College Students
- Assessment of Vascular Function: Changes throughout the Menstral Cycle
Vascular Ion Channel Research Laboratory
Our research focuses on how vascular ion channels regulate vascular tone in health and disease. Our goal is to identify the role of ion channels in mechanisms of vascular dysfunction in the presence of independent cardiovascular risk factors (e.g. obesity) in order to provide novel targets for preventing the advancement of severe disease states.
- Obesity-induced endothelial Kir channel impairment in visceral adipose arteries
- Visceral vs. subcutaneous adipose in vascular ion channel dysfunction
- Exercise and diet as lifestyle interventions to improve ion channel function
Vascular Physiology Research Laboratory
Our research focuses on studying vascular function/dysfunction in healthy and diseased states, with particular emphasis on chronic kidney disease, and vascular responses to exercise and diet. Our research examines macro- and microvascular function as well as arterial stiffness in humans and animal models.
- Chronic Kidney Disease Research
- Mitochondria Function in Chronic Kidney Disease
- Vascular Effects of Dietary Salt in Humans with Salt-Resistant BP: Dietary Counseling Study
- The Effect of Acute Exercise on Pulsatile Load in Healthy Aging
- Cardiovascular Effects of High-Intensity Interval Training and Moderate-Intensity Continuous Training
- The Effect of Shear Stress and Urea on Endothelial Cationic Amino Acid Transporter-1 (CAT-1) and Endothelial Nitric Oxide Synthase (eNOS)
Womens Cardiovascular Research Laboratory
Our research focuses on cardiovascular health in women throughout their lifespan. We study mechanism contributing to vascular dysfunction in women as they age, and the role estrogen may play in maintaining vascular health, as well as blood pressure regulation in women to understand why the prevalence of hypertension is greater in women after menopause.
- Impact of Estrogen on Vascular Function in Women
- Mechanisms contributing to hypertension in postmenopausal women