Christopher R. Martens

Research Interests

Aging is the primary risk factor for the development of Alzheimer’s disease (AD), which is rapidly becoming a global health concern. Cardiovascular risk factors such as increased blood pressure and stiffening of the elastic arteries occur with aging have been shown to increase risk of cognitive impairment and AD in older adults.  My laboratory is interested in understanding the mechanisms by which impaired vascular function contributes to cognitive declines with aging and developing novel pharmacological, lifestyle and dietary (e.g., nutraceutical) interventions to delay or reverse age-associated cognitive decline by increasing blood flow to the brain.


  • B.S., University of Delaware, Exercise Science
  • Ph.D., University of Delaware, Applied Physiology
  • Postdoctoral Fellowship, University of Colorado Boulder, Physiology of Aging


  • KAAP 440 – Topics in Exercise Science (Healthy Aging)

Current Funding

NIH K01AG054731    |    Martens (PI)     |     07/16/2017-03/31/2018
NAD+ Therapy for improving memory & cerebrovascular function in patients with MCI.

The goal of this study is to determine the effects of lowering blood pressure and aortic stiffness with nicotinamide riboside supplementation on cerebrovascular and cognitive function in patients with amnestic mild cognitive impairment.

Christopher R. Martens
Assistant Professor

201Z Health Science Complex

Neurovascular Aging Laboratory
Applied Physiology PhD Faculty Advisor