Determining the early stages of the HIV life-cycle using the computational microscope.

Presenters: Chaoyi Xu, of Juan Perilla’s Research Group

During the first hour of this month’s HPC Symposium, Graduate Assistant Chaoyi Xu of Juan Perilla’s Research Group will clarify how HIV host pathogens exert a controlling influence on viral particle trafficking through cytoplasm. Additionally, Xi will discuss the energetics associated with viral RNA reverse transcription and will introduce the multi-scale framework that allows his team to determine the structure of capsid assemblies.

Xu notes, “Importantly, our approach relies on current petascale supercomputers to reveal the molecular details of biological events which occur on the second time-scale and span over several micrometers in magnitude – the latter involving systems containing multi-million atoms.”

More information about the 2nd generation of the Caviness cluster will be revealed during the discussion portion of the symposium.

Refreshments will be served.