Dissertation Defense Schedule

Academic Excellence

Sharing original dissertation research is a principle to which the University of Delaware is deeply committed. It is the single most important assignment our graduate students undertake and upon completion is met with great pride.

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PROGRAM | Biomedical Engineering

Examining Nanoparticle Based Systems for Applications in Maternal/Fetal Health

By: N’Dea Irvin-Choy Chair: Emily Day Co-Chair: Jason Gleghorn

ABSTRACT

Dissertation Abstract: In recent decades, researchers have extensively utilized nanoparticle-based drug carrier systems for various diseases such as cancer1–3 and COVID-194–6. However, only recently has the exploration of these systems have been used for maternal/fetal health applications. The development of nanomedicines capable of targeting therapies to specific reproductive organs while minimizing off-target delivery and toxicity would have a transformative impact on managing conditions affecting pregnant women and their unborn children. This thesis provides insight into the potential of nanomedicine for maternal/fetal health applications. It will achieve this by examining the distribution of nanoparticles in pregnant murine models following systemic or vaginal delivery and demonstrating how nanoparticle drug release profiles can be adjusted to regulate bacterial growth kinetics, using bacterial vaginosis (BV) as a model disease. The completion of these objectives contributes new knowledge and guide future developments in utilizing nanoparticles as tools for maternal/fetal health applications.

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The Process

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Visit our “Step-by-Step Graduation Guide” to take you through the graduation process.From formatting your Dissertation to Doctoral Hooding procedures.

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Dissertation Manual

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Defense Submission Form

This form must be completed two weeks in advance of a dissertation defense to meet the University of Delaware Graduate and Professional Education’s requirements.

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