John Peloquin, Ph.D.

Associate Scientist
University of Delaware
peloquin@udel.edu
LinkedIn

EDUCATION
Ph.D. Bioengineering, 2016,
University of Pennsylvania
M.Eng. Biomedical Engineering 2010,
Cornell University
B.S. Materials Science and Engineering 2009,
Cornell University

Mechanisms of General 3D Joint Loading

The knee meniscus supports multiaxial 3D joint loads. Fluid pressurization is thought to substantially contribute to its ability to support these loads without damage.  However, some combinations of load may compromise this fluid load support.  I study how the meniscus’ load support mechanisms change between loading conditions.

Damage Initiation and Propagation

Tensile failure of meniscus.Fibrous tissues such as knee meniscus and intervertebral disc annulus fibrous have a tendency to develop tears and other damage, compromising function and causing pain. I work to identify how and why tears and damage occur so that their progression can be slowed or prevented entirely.

Intervertebral Disc Strain

I measure 3D strain fields from MRI images of living humans using digital image correlation techniques.  This provides new information about how disc function is disrupted by aging and degeneration.

Recent Publications

  1. Kyle D. Meadows, John M. Peloquin, Madeline Boyes, Brendan D. Stoeckl, Jamie Benson, Sonia Bansal, David R. Steinberg, Miltiadis H. Zgonis, Thomas P. Schaer, Robert L. Mauck, Dawn M. Elliott. (2025) “Time-dependent changes in medial meniscus kinematics and attachment strength after anterior root injury and repair in a large animal model.” Journal of Orthopaedic Research, 43 (2025), 692–702. doi: 10.1002/jor.26022
  2. John M. Peloquin and Dawn M. Elliott. (2024) “Global and local identifiability analysis of a nonlinear biphasic constitutive model in confined compression.” Journal of the Royal Society Interface, 21 (2024), 20240415. doi: 10.1098/rsif.2024.0415
  3. Milad I. Markhali, John M. Peloquin, Kyle D. Meadows, Harrah R. Newman, Dawn M. Elliott. (2024) “Neural Network Segmentation of Disc Volume from Magnetic Resonance Images and the Effect of Degeneration and Spinal Level.” JOR Spine, 7, e70000. doi: 10.1002/jsp2.70000
  4. John M. Peloquin, Michael H. Santare, Dawn M. Elliott. (2023) “Volume Loss and Recovery in Bovine Knee Meniscus Loaded in Circumferential Tension.” Journal of Biomechanical Engineering, 145, 071009. doi: 10.1115/1.4062142
  5. Kyle D. Meadows, John M. Peloquin, Milad I. Markhali, Miltiadis H. Zgonis, Thomas P. Schaer, Robert L. Mauck, Dawn M. Elliott. (2023) “Acute Repair of Meniscus Root Tear Partially Restores Joint Displacements as Measured With Magnetic Resonance Images and Loading in a Cadaveric Porcine Knee.” Journal of Biomechanical Engineering, 145, 081002. doi: 10.1115/1.4062524
  6. Kyle D. Meadows, John M. Peloquin, Harrah R. Newman, Peter Cauchy, Edward J. Vresilovic, Dawn M. Elliott. (2023) “MRI-based Measurement of Disc Mechanics in a Young Population due to Flexion, Extension, and Diurnal Loading.” JOR Spine, e1243. doi: 10.1002/jsp2.1243.
  7. Harrah R. Newman, John F. DeLucca, John M. Peloquin, Edward J. Vresilovic, Dawn M. Elliott. (2021) “Multiaxial Validation of a Finite Element Model of the Intervertebral Disc with Multigenerational Fibers to Establish Residual Strain.” JOR Spine, e1145. doi: 10.1002/jsp2.1145