Call for COBRE Pilot Projects

UD’s new NIH Center for Biomedical Research Excellence (COBRE) in Cardiovascular Health is pleased to announce a call for COBRE pilot research grants to expand and enhance the scientific goal of the center, which is to catalyze cardiovascular health research at UD. The COBRE pilot projects will provide funding for a one-year period that will allow investigators to develop more substantial external NIH support from individual or multi-investigator proposals.

We anticipate funding 2-3 projects this year. Projects will be awarded for 1 year, with a budget of $50,000 in direct costs.

Estrogen levels and heart disease

Estrogen levels and heart diseaseDELAWARE PUBLIC MEDIA — As women age, their risk for cardiovascular disease becomes higher than men. According to, it kills one in three women each year and affects over 44 million women in the United States. University of Delaware Physiologist Megan Wenner wants to understand the role changes in estrogen play in leading to this higher risk of heart disease. Read more >>

Deciphering hormones

Deciphering hormonesHormones are the chemical envoys for our bodies. They communicate with our brains, heart, bones, muscles and, yes, reproductive organs. University of Delaware physiologist Megan Wenner is working to understand how sex hormones influence vascular function. She’s focused specifically on comparing estrogen effects in young and postmenopausal women. What happens after menopause when hormone levels drop dramatically? Are therapy interventions safe or not? Read more >>

UD lands multi-year Center of Biomedical Research Excellence grant

Cardiovascular disease remains the number one cause of death for both men and women across the United States. The state of Delaware is in the bottom half of states for coronary heart disease death rates.

To help tackle this problem, the National Institute of General Medical Sciences at the National Institutes of Health has awarded the University of Delaware a five-year, $11.6 million grant to support a Center of Biomedical Research Excellence (COBRE) in cardiovascular health.

Dave Edwards, associate professor in the Department of Kinesiology and Applied Physiology, is the principal investigator.  Read more >>

Research provides new insights into bone biology

Rhonda Prisby is conducting research on bone biology.

Bone marrow, the spongy tissue inside long bones, produces new blood cells and helps the lymphatic system work properly.  But it may also turn out to be a progressively hostile microenvironment that induces vascular dysfunction and ossification, or hardening, of blood vessels. Read more >>