Discovery of Molecular Probes and Therapeutic Leads

An NIH Center of Biomedical Research Excellence


August 2020. Phase II was awarded, extending the award for 5 more years with additional funding of $11.9M.

October 2019. Phase I graduate Eric Bloch received a research award from the Department of Energy entitled Methane and Hydrogen Storage with Cage-Based Composite Materials.

August 2019. Phase I investigator April Kloxin received the prestigious NIH Director’s New Innovator Award for her project entitled Unraveling Fibrosis with Dynamic Microenvironments and Molecular Tools.

August 2019. Phase I graduate Yvette Yien received an NIH R35 Maximizing Investigators’ Research Award for Early Stage Investigators for her project entitled Regulation of Heme Synthesis by Mitochondrial Proteins.

August 2019. Phase I graduate Catherine Grimes will be the recipient of the David Y. Gin New Investigator Award from the American Chemical Society in 2020.

May 2019. Phase I graduate Mary Watson received an NIH R35 Maximizing Investigators’ Research Award (MIRA)  entitled Harnessing Alkyl Amines and Alkyl Alcohols in Cross-Coupling Reactions.

February 2019. PI Joseph Fox’s NIH R01 proposal, Toolkit for Fast, Multipurpose and Inducible Bioorthogonal Chemistry, has been selected for funding by NIGMS.

January 2019.  PI Joseph Fox received a new research award from The Delaware Bioscience Center for Advanced Technology (CAT) program (State of Delaware).

December 2018. PI Joseph Fox received a research award from Pfizer entitled Impacting Chemical Biology through Synthetic Excellence.

November 2018. Phase I graduates Donald Watson and Mary Watson received a major award from Unidel foundation for core facility enhancement entitled High-Throughput Instrumentation Core to Accelerate Discovery.

November 2018.  Pilot investigator Ramona Neunuebel received a new NIH 21 award from NIAID entitled Characterization of Legionella effectors targeting host membrane compartments.

November 2018.  Phase I investigator Eric Bloch received a University of Delaware Research Foundation Award entitled Electrochemical Synthesis of Metal-Organic Frameworks.

October 2018.  Phase I graduate Mary P. Watson received a research award from Pfizer entitled Transforming Alkyl Amines to Alkyl Arenes: Sp2/Sp3 Cross-Coupling of Alkyl Amines to Aryl Halides/Carboxylic Acids and Its Application to Parallel Medicinal Chemistry.

August 2018.  Project Investigator Yvette Yien received an NIH R03 award from NIDDK entitled Control of Porphyrin Synthesis by ClpX: a Novel Regulatory Node in Erythroid Heme Synthesis.