Summer  2025


Congratulations to Liam O’Grady on being invited to present his work on the Enantioselective Total synthesis of (–)-Psiguadial A at the ACS Graduate Research Symposium.


Spring  2025


Congratulations Nicole Kretekos on receiving a GSK summer internship!

Check out our new paper! Enantioselective Total Synthesis of (–)-Psiguadial A” By Liam P. O’Grady, Marcel Achtenhagen, Michael F. Wisthoff, Robert S. Lewis, Katarina Pfeifer, Weifeng Zheng, Maxwell I. Martin, Glenn P. A. Yap, William J. Chain.

Congratulations to Dr. Alexandre Ziegelmeier on successfully defending his Ph.D. on “Efforts Toward the Total Synthesis of Premnalatifolin A and Martinelline!”

 

Congratulations to Jasmine Bioteau on defending her senior thesis!

 

Congratulations to Shelby Cooper and Kyle Hess on becoming Ph.D. candidates and passing their first committee meetings!

 


Fall  2024


Congratulations to Dr. Tyler Swanson on successfully defending his Ph.D. on “Cyclizations of Aniline N-Oxides to Give Tetrahydroquinoline and Related Polycyclic Scaffolds

 


Summer  2024


Congratulations to Jasmine Bioteau on completing a summer research rotation at the University of San Diego working with Professor Tim Clark.


Spring  2024


Congratulations to Alisha Wang on defending her senior thesis!

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Congratulations Nicole Kretekos on becoming a CBI fellow!

Congratulations Alex and Tyler on receiving summer internships at Prelude Therapeutics!

Congratulations to Nicole Kretekos and Leah white on passing their first committee meetings and becoming Ph.D candidates!


Fall  2023


Congratulations to Dr. Elijah Hudson on successfully defending his Ph.D. on “The Development of New Englerin-Inspired Chemotherapeutic Drug Candidates and Tool Compounds and the Synthesis of an Acyldepsipeptide Fluorescent Probe

Congratulations to Shelby Cooper and Kyle Hess who joined us as graduate student researchers!

The Chain lab was ready to build connections and bonds during the first year laboratory practical!

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Summer  2023


Welcome to Shelby Cooper, joining the Chain Group for summer research! 


Spring  2023


 Congratulations to Liam and Alex on receiving the Elizabeth Dyer Award for excellence in teaching!

 


Fall  2022


Welcome to Nicole Kretekos and Leah White to the Chain Group as graduate student researchers!

Check out our new paper! “Transformation of a N,N-Dimethylaniline N-oxide into a Tetrahydroquinoline Scaffold via a Formal Polonovski-Povarov Reactionby Elizabeth L. Isaac, Lauren N. Tumbelty, and William J. Chain

Check out our new paper! “Recent Developments with Icetexane Natural Products” by Ali Amiri Naeini, Alexandre A. Ziegelmeier, and William J. Chain.


Summer  2022


Group outing to White Clay Creek Concert 

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Welcome to Nicole Kretekos, joining the Chain Group for summer research! 


Spring  2022


Congratulations to Matt Kaganovich on successfully defending his honors undergraduate thesis!

Congratulations to Finn Davis on receiving his Bachelor’s of Science degree!

Congratulations to Dr. Ali Amiri Naeini on successfully defending his Ph.D. on “Synthetic Efforts Toward the Total Synthesis of Premnalatifolin A & Monomeric Unnatural Icetexane Analogs” !

The Chain group at the CBI Trivia night!

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Congratulations to Tyler Swanson and Alex Ziegelmeier on passing their first Committee meetings!

Welcome to Alisha Wang as an undergraduate researcher!


Fall  2021


 

Congratulations to Dr. Marcel Achtenhagen on successfully defending his Ph.D. on “Synthetic Efforts Toward the Total Synthesis of Psiguadial A & HPLC Method Development for Artemisinin Metabolites” !

Check out our new paper! “Electrochemically Mediated Oxidation of Sensitive Propargylic Benzylic Alcohols” By, Hatch, C.E., Martin, M.I., Gilmartin, P.H., Xiong, L., Beam, D.J., Yap, G.P.A., Von Bargen, M.J., Rosenthal, J., Chain, W.J.

Congratulations to Dr. Chad Hatch on successfully defending his Ph.D. on “Electrochemically Enabled Total Synthesis of Anti-Cancer Natural Products: The Total Synthesis of (±)-Paucilflorol and (±)-Isopauciflorol F, Electrooxidative Methods Development, and Effort Toward a Versatile Total Synthesis of 12-Deoxyphorbol” 


Summer  2021


Welcome Liam O’Grady as a graduate student researcher!

Welcome Kelly Modi as a high school summer research intern!


Fall 2020


Welcome Alex Ziegelmeier and David Detloff as graduate student researchers!


Spring  2020


Congratulations to Elijah Hudson and Rachel Putnik on completion of their first committees! 

Congratulations to Katarina Pfeifer on successfully defending her honors undergraduate degree!

Congratulations to Dani Beam on receiving her Bachelor’s of Science degree!  

Congratulations Dr. Hayley Reed for successfully defending her Ph.D. on “Aromatic Functionalization and Heterocycle Synthesis via Aniline N-Oxides” !


Fall 2019


Welcome Tyler Swanson as a graduate student researcher!


Spring 2019


 

Congratulations to Ali Amiri Naeini for completion of his first committee meeting!

 

Congratulations to Marcel Achtenhagen and Chad Hatch for completion of their first committee meetings!


Fall 2018


Welcome Elijah Hudson, Elizabeth Isaac, Rachel Putnik, and Lauren Tumbelty as graduate researchers!


Summer 2018


Check out our publication on Synthesis of Halogenated Anilines by Treatment of N,N‑Dialkylaniline N‑Oxides with Thionyl Halides!

Check out our  publication on Transformation of N,N-Dimethylaniline N- Oxides into Diverse Tetrahydroquinoline Scaffolds via Formal Povarov Reactions!


Spring 2018


Congratulations to Marcel Achtenhagen, Chad Hatch and Melody Moy for their completion of cumulative exams!

A Strategy Toward Icetexane Natural Products was published in European Journal of Organic Chemistry.

Congratulations to Tyler Paul on receiving the 2018 James A. Moore Undergraduate Award in Organic Chemistry.  We also congratulate him on graduating with B.S. in Chemical Engineering from the University of Delaware, Good luck on your future career!

2018 Undergraduate Award Recipients
Tyler Paul is in 3 row on the far right

Congratulations to Dr. Mohammad Al-Amin  on accepting the job offer to work for Adesis! We wish you the best of luck with your future career.

Welcome Michael Cali, Ethan Weinstein and Katarina Pfeifer as an undergraduate researchers!


Winter 2017-2018


Welcome  Michael Moreno as an undergraduate researchers!


Fall 2017


Congratulations to Dr. Zhenhua Wu  on accepting the job offer to work for Adesis! We wish you the best of luck with your future career.

Welcome Tim Bush and Matt Von Bargen to the Chain Research Group!

Congratulations to Dr. Michael Wisthoff and best of luck on your future career!

Dr. Michael Wisthoff at his PhD Defense

Congratulations to Natasha Kowaleuski and Hayley Reed for advancing to  PhD candidacy!


Summer 2017


Congratulations to Chad Hatch for being awarded the Graduate University Scholars Fellowship!

Congratulations to the Aniline Subgroup on being awarded a NSF grant for their continued research exploring metal-free functionalization of anilines!

Welcome Tim Bush and Matt Von Bargen as summer researchers!


Spring 2017


Check out a recent publication by our group, Englerins: A Comprehensive Review. J. Nat. Prod. 201780, 771–781.

Congratulations to Natasha Kowaleuski and Hayley Reed for their completion of cumulative exams!


Fall 2016


Welcome to Marcel Achtenhagen, Chad Hatch and Melody Moy to the Chain Research Group!

Welcome Tyler Paul as an undergraduate researcher!

Congratulations to Chad Hatch for being awarded the Graduate University Scholars Fellowship!

Welcome to Dr. Zhenhua Wu to our group as a postdoctoral fellow!


Summer 2016


Welcome to Ali Amiri Naeini to the Chain Research Group!

Congratulations to Daniel Moon on the completion of his master’s thesis!

Welcome to Marcel Achtenhagen as a summer researcher!


Spring 2016


Welcome to Chad Hatch to the group as a researcher!


Fall 2015

Welcome Natasha Kowaleuski and Hayley Reed to the Chain Group!

Welcome Dr. Mohammad Al-Amin to our group as a postdoctoral fellow!

William Chain moved the lab from University of Hawaii at Manoa to the University of Delaware with 2 graduated students, Daniel Moon and Michael Wisthoff.