Fromen Research Group

Engineering Particle-Lung Interactions

Welcome to the Fromen Research Group!  Our research is all about the lungs. We seek to advance understanding of the unique environment of the airways, from fluid dynamics to mucosal immunology. Armed with this foundation, we develop new therapeutics and analytical tools to treat a range of diseases specific to the lungs.



April Updates

Congrats to Bader on the Fromen Lab’s first pre-print “Nanoparticle Internalization Promotes the Survival of Primary Macrophages“! We are very excited to share this work and have it available for everyone to read.

We also have a number of belated congratulations for our awesome Fromen lab undergraduate seniors:

Congrats to Emma Peterman on being awarded a 2021 NSF GRFP Fellowship!!! And congratulations on your decision to attend the Chemical Engineering Program at MIT in the fall!

Congrats to Lucas Attia on accepting the 2021 DOE Computational Science Graduate Fellowship (CSGF) and for also being recognized as a 2021 NSF GRFP Awardee! And congratulations on your decision to attend the Chemical Engineering Program at MIT in the fall!

Congrats to Premal Patel for accepting your job offer at Veeva Systems!

We are so proud of our senior undergrads and wish them all the best on their next adventures! We’re also happy that we don’t have to say goodbye quite yet… You can hear about their ongoing research and attend their senior thesis presentations happening in early May (contact Prof Fromen for connection details)

  • Emma’s presentation will be Wed May 12 at 3pm
  • Premal’s presentation will be Thurs May 13 at 3:45 pm
  • Lucas’s Presentation will be Fri May 14 at 8am

We are also excited to welcome three new undergraduate students into the Fromen lab this semester!  Welcome to Aaron Lam, Simone Sabnis, and Saurav Padhye! We are excited that all three of you will be joining us for the summer as UD Summer Scholars!

 

Two papers!

Congrats to the Fromen lab members for two new publications accepted this past week!

“Biomaterials-Based Opportunities to Engineer the Pulmonary Host Immune Response in COVID-19” was accepted in ACS Biomaterials Science & Engineering. In this review article, we document the current understanding of the immune response in the lung during COVID-19 infection and offer a collection of promising particle engineering strategies as potential therapeutic solutions. Congrats to Bader, Zach, Kartik, April, and Cathy on this publication!

“Check the Gap: Facemask Performance and Exhaled Aerosol Distributions Around the Wearer” was accepted in PLOS ONE. In this work, we demonstrate changes in exhaled aerosol distributions with and without facemasks and showcase how important the fit around the face is for different facemask types. Our most important finding: particle size distributions escaping from gaps around a facemask are on average larger than the normal particle size distribution without a mask – this points to a secondary benefit of wearing a mask where it not only traps particles, but also promotes aerosol evolution into larger particle sizes that can settle out of the airstream faster. So, keep masking up! Congrats to Emily, Zach, Ian, and Cathy on this publication!

Head over to the Publication page for links to the papers, which will be updated as soon as the articles appear online.

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