Christopher Price, Ph.D.
5 Innovation Way
Suite 200, Room 106
Newark, DE 19711
Ph.D., Biomedical Sciences, 2008, Mount Sinai School of Medicine
B.Sc., Biomedical Engineering, 2000, Boston University
Life & Health Sciences
AREAS OF SPECIAL INTEREST
Dr. Price’s work in musculoskeletal biology and bone adaptation has been recognized nationally and internationally as the recipient of the Orthopaedics Research Society’s prestigious New Investigator Recognition Award (2010), and Young Investigator Awards from the International Bone Fluid Flow Workshop (2010), the International Chinese Hard Tissue Society (2010), the International Bone and Mineral Society International Sun Valley Workshop on Skeletal Biology (2009), and the American Society for Bone and Mineral Research-National Institute of Arthritis and Musculoskeletal and Skin Diseases Bone Quality Meeting (2005).
Dr. Price’s research focuses on the role that load-induced solute transport and fluid flow within both bone and cartilage has on the development, maintenance, adaptation, and degeneration of those tissues, especially with respect to the disease etiology of osteoporosis and osteoarthritis. His current research includes investigations into the biology and mechanics of bone and cartilage adaptation, the direct quantification and modeling of fluid flow within healthy and diseased tissues, the development of novel advanced imaging techniques for the investigation and solute/fluid transport in biological tissues, the exploration of novel imaging-based functional markers of musculoskeletal degeneration and disease, and the rational bio-mechanically inspired development of treatment and prevention paradigms for both bone loss and cartilage degeneration.
Price, C., Zhou, X., Li, W., Wang, L., 2011, Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: direct evidence for load-induced fluid flow. JBMR, 26(2): 277-285
Li, W., Gardinier, J.D., Price, C., Wang, L., 2010 Does blood pressure enhance solute transport in the bone lacunar-canalicular system? Bone, 47(2): 353-359
Price C., Li, W., Novotony, J.E., Wang, L., 2010, An In-situ Fluorescence-Based Optical Extensometry System for Imaging Mechanically Loaded Bone, Journal of Orthopaedic Research, 28(6), 805-811.
Jepsen K.J., Price C., Silkman L.J., Nicholls M.A., Nasser P., Hu B., Hadi N., Alapatt M., Stapleton S.N., Kakar S., Einhorn T.A., Gerstenfeld L.C., 2008. Genetic variation in the patterns of skeletal stem cell differentiation and progression during endochondral bone formation affects the rate of fracture healing. Journal of Bone and Mineral Research, 23(8), 1204-1216.
Price, C., Herman, B.C, Lufkin, T, Goldman, H.H., Jepsen, K.J. 2005. Genetic variation in bone growth patterns defines adult mouse bone fragility. Journal of Bone and Mineral Research Nov; 20(11):1983-91.