News & Highlights
Register now (by August 12th) for the
2016 MATERIALS CHARACTERIZATION WORKSHOP
August 23-24, 2016
University of Delaware Pearson Hall & Harker Labs (ISE Building)
For more information:
“We know that the Human Genome Project has changed the landscape radically, forever! And now we’re going to do the same thing in Organ-on-a-Chip and Regenerative Medicine, by bringing solutions, at scale, to the world’s population.”
VanDam, D. (2016, July 12). “How to Change the World with 200 People: Organ-On-a-Chip.” Retrieved from https://www.linkedin.com/pulse/how-change-world-200-people-organ-on-a-chip-dawn-vandam.
Research team including UD BME affiliated faculty receive NIH grant to create a realistic model of human vocal cords!
Research team, including UD BME and BME affiliated faculty, receives NIH grant to create a realistic model of human vocal cords!
See the UDaily article here: http://www.udel.edu/udaily/2016/june/vocal-cord-research/
Biomedical Engineering welcomes our new administrative support team member, Ja’Nise Farris.
|For the third year in a row, the students of Biomedical Engineering have won the Dean’s cup. This award is earned by the department in the College of Engineering with the largest percentage of student donations.|
A postdoctoral researcher position in the field of cancer nanomedicine is available in the laboratory of Emily Day, Ph.D. The candidate will develop nanoparticles for treatment of cancer, and test these nanoparticles using in vitro and in vivo models of disease. The laboratory is located at the University of Delaware in Newark, Delaware, and is affiliated with the Department of Biomedical Engineering at the University of Delaware, as well as with the Center for Translational Cancer Research at the Helen F. Graham Cancer Center & Research Institute. More information about the Day Laboratory is available at: http://sites.udel.edu/daygroup.
BME Research Symposium
June 20, 2016 at Embassy Suites Newark
Biomedical Engineering will hold a research symposium that features the breadth of biomedical research in Delaware and builds new research collaborations. Faculty from across UD and nearby institutions will present 5-minute overviews of their research and there will be ample time for networking at student research poster presentations. We invite all students, faculty, and external professionals who are interested in and those who currently collaborate with the Biomedical Engineering field to register their attendance. Full and partial registration (free) can be completed at the BME Research Symposium Registration Page – online registration closes 6/13. Please contact Ja’Nise Farris (302-831-4578) in the BME office for any questions or issues with registration.
|Jason Gleghorn has received a three-year grant from the Biomechanics and Mechanobiology Program of the National Science Foundation to study smooth muscle contractions that occur in the developing mammalian lung. This research will determine the cellular and molecular mechanisms underlying airway smooth muscle contractions and their role in airway branching. Deeper understanding of the mechanisms that cause the growth of the airways is of importance for understanding lung development in general and also for predicting, preventing, and repairing structural birth defects.|
Kenneth Barner, professor and chair of the Department of Electrical and Computer Engineering at the University of Delaware, has been named an IEEE Fellow for his contributions in the area of nonlinear signal processing.
IEEE Fellow is the highest grade of membership and is recognized by the technical community as a prestigious honor and an important career achievement. The honor is conferred on only one-tenth of one percent of the total voting membership each year.
Students in Dr. Emily Day’s research group have published a paper in the International Journal of Nanomedicine describing a new way to sensitize cancer cells to chemotherapy. Chemotherapy resistance in cancer is often attributed to cancer cells’ ability to keep drugs outside the cell. The Day lab has shown that this resistance mechanism can be overcome by heating cancer cells with photothermal therapy, a technique in which nanoparticles delivered to cancer cells produce heat upon exposure to light. The Day lab’s results demonstrate that applying heat to cancer cells with photothermal therapy can increase drug accumulation in the cells, which in turn improves treatment effect. The student co-authors on the paper include Brittany Fay, who received her B.S. in Biomedical Engineering at UD in May 2015, and Jilian Melamed, current Biomedical Engineering Ph.D. student. This research was supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH), by the Delaware INBRE program with a grant from NIGMS of the NIH, by the University of Delaware Summer Scholars Program, and by the Department of Defense through a National Defense Science and Engineering Graduate Fellowship.
The University of Delaware’s Babatunde Ogunnaike has been named a fellow of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society. The association bestows the title of AAAS Fellow on members who are selected by their peers for scientifically or socially distinguished efforts to advance science or its applications.
Ogunnaike, the William L. Friend Chair of Chemical Engineering, was recognized for his distinguished contributions to process control systems, process engineering practice, and systems engineering education. His work addresses both industrial processes and systems biology.
The Department of Biomedical Engineering at the University of Delaware hosted the inaugural Mid-Atlantic BME Grad Fair on Nov. 14 in the Harker Interdisciplinary Science and Engineering Laboratory. The event, which included graduate program exhibits and undergraduate research posters, was held to give prospective BME graduate students access to information and foster networking with programs in the region.
|Dawn Elliott traveled to Adelaide Australia to collaborate with John Costi over summer 2015 at the Medical Device Research Institute at Tonsley under a Flinders Visiting International Research Fellowship. There, Elliott was able to us a hexapod robot that can subject discs to realistic loading scenarios. The available testing capabilities of Costi’s lab complemented Elliott’s research.Read More|
A paper co-authored by BME faculty member Jason Gleghorn appears in the current issue of the Proceedings of the National Academy of Science, published July 28, 2015. The paper entitled “Mechanically patterning the embryonic airway epithelium” uses a combination of 3D culture experiments and theoretical modeling to understand how the airways within the developing lung form such complex and repeatable architectures that are conserved within a given species and critical for survival. They identified a growth-induced buckling mechanism that can control the initiation and pattern of new epithelial branches. Tuning epithelial growth changes the wavelength of the bucking instability and thereby the branching pattern. These findings emphasize the role of mechanical forces during morphogenesis and indicate that in addition to genetic programs, physical cues also regulate the spatially patterned cell behaviors that underlie organ assembly in the embryo. Read More Here
|Dr. Liyun Wang, Associate Professor of Mechanical Engineering, has been awarded an NIH grant to continue research on exercise and bone quality. This five-year $1.9-million grant is a competitive renewal of her previous NIH grant on transport mechanisms in mineralized bone. With this award Wang aims to identify new molecular targets for preventing and slowing the onset of osteoporosis. Partnerships on this research include Cindy Farach-Carson (Rice University), Lucas Lu (Mechanical Engineering at UD), Catherine Kirn-Safran (Biological Sciences at UD), and Sherry Lu from the University of Pennsylvania. Read More Here.|
|David Martin, Karl W. and Renate Böer Professor of Materials Science and Engineering, was named a 2015 American Chemical Society (ACS) Fellow. The ACS Fellows program recognizes members for outstanding achievements in and contributions to science, the profession, and ACS. Read More Here.|
|John Slater recently published a high impact paper in ACS Nano that details a new high-resolution, image-based, cell-derived patterning strategy to produce arrays of homogeneous cells that display the cellular architecture with the anatomical and functional properties of the user-chosen cells that the patterns were derived from. This strategy will be useful in producing a platform for more homogeneous cell populations for high-throughput cellular assays.|
At the First Step Grand Challenges Program Symposium, held on the UD STAR campus, BME undergraduate students were awarded second and third place in the Health track. The SimUCath design team won second place for their wearable training system for urinary catherization, earning a $1,000 award. Third place was awarded to Amira Idris for her invention Vibrosocket, which is a device that increases tissue activity for lower limb amputees, earning a $500 award. Read more.
Jill Higginson and her team have received a 5-year educational grant from NIH to incorporate practical clinical design experience into UD’s Biomedical Engineering curriculum. The plan is to expand the BME interdisciplinary senior design program to include clinically motivated projects identified during previous clinical immersion experiences. Within the context of this design project, students will identify the significance of the unmet clinical need, determine the impact of finding a practical solution, outline the design constraints, and generate a working prototype as a solution to the unmet clinical need. Read more.
April Kloxin thinks science rocks, so her research group is reaching out to the public through an interactive kiosk called Mimicking Nature at the Delaware Museum of Natural History, as well as through a radio show called Science Rocks! on the University’s student-run radio station, WVUD. Read more.
Jason Gleghorn has received a Ralph E. Powe Junior Faculty Enhancement Award from Oak Ridge Associated Universities (ORAU), a network of 115 research-oriented schools around the nation, to study lung development. Read more.
Dawn Elliott was awarded the Van C. Mow Medal by ASME for significantly advancing the field of biomedical engineering through her contributions in musculoskeletal tissue structure-function research, her student mentorship with a focus on mentoring women, and her leadership in the bioengineering division of ASME. She also received the ORS Outstanding Achievement in Mentoring Award for her exceptional achievement in mentorship and advocacy on behalf of new investigators in orthopedic research. Read more.
At UD’s 12th annual Biomechanics Research Symposium hosted by CBER on May 8, BME grad students won both awards for podium presentations of their research. Ashutosh Parajuli won first place for presenting “A Cross-Sectional Age-Wise Assessment of Morphology and Bone Formation in Perlecan-Deficient Mice”; Michael David won second place for presenting “Detailed Quantification of Early Structural Joint Changes in the Murine Destabilized Medial Meniscus Model of Post-Traumatic Osteoarthritis.” Dawn Elliott delivered keynote address at the event. Read more.
BME undergrad Arvind Annamalai is part of the Malawi Water Project, one of 3 student projects chosen to receive seed funding from the Clinton Global Initiative University (CGI U) this past March. The other 2 projects chosen from UD were the Little Bob Initiative and FEMpower. Read more.
2014 Interdisciplinary Senior Design Team SimUCath was awarded FIRST prize at the University of Minnesota Medical Devices Conference, beating out an impressive field of teams across the country. SimUCath is a novel system that allows healthcare professionals to safely train to perform urinary catherizations on live actors. Read more.
BME grad student Keely Heinz has received the 2015 Laird Merit Fellowship that is given to one first year grad student in the College of Engineering each year to honor the memory of George W. Laird. Keely is currently pursuing her BME PhD in John Slater’s lab, researching the fabrication of biomimetic microfluidic hydrogel constructs for advanced cell culture platforms. Read more.
The report, America’s Knowledge Economy: A State-by-State Review, issued by the Council of State Governments and the academic publisher Elsevier, assesses research output and impact from 2004 to 2013. The scholarly research publications produced in each state are a key barometer for innovation. Delaware had the second highest rate of peer-reviewed publication production nationwide. Delaware researchers produced 11.4 publications per million dollars in research and development (R&D) funding spent. Read more.
UD will be getting Delaware’s first functional MRI (fMRI) in early 2016. This specialized type of MRI will enable researchers to see which structures and neural networks in the brain are being used while engaged in a particular task. “This type of imaging is critically important, not just for psychology but also for biomedical engineering and health sciences,” said Dawn Elliott, director of UD’s biomedical engineering program. “Having this here will be a big benefit to my research and to many others.” Read more.
A paper co-authored by Emily Day, “miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma”, has been selected as the cover of an upcoming issue of Genes & Development. The paper identifies a small RNA molecule called miR-182 that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor. The researchers used nanoparticles called spherical nucleic acids to safely deliver miR-182 across the blood-brain/blood-tumor barriers to reach tumor cells where they directly suppressed multiple oncogenes at once, increasing cancer cell death, reducing tumor growth, and improving overall survival. This approach offers a novel strategy for therapeutic intervention in GBM.
BME grad student Jilian Melamed was awarded a National Defense Science and Engineering Graduate (NDSEG) Fellowship. Jilian’s PhD research involves developing a nanoparticle-based treatment to overcome the resistance of cancer cells to chemotherapy. Read more.
At a Healthcare Hackathon hosted by the College of Health Sciences, BME undergrads were among the four student teams who presented their ideas to a diverse audience of state officials, Christiana Care physicians, state medical reps and UD faculty and staff. Read more.
April Kloxin and Christopher Kloxin have been awarded Strategic Initiative Grants from the UD Research Foundation (UDRF) to support their work on bone health and medication delivery, respectively. Read more.
Dawn Elliott is one of two Orthopaedic Research Society (ORS) members to receive the new ORS Outstanding Achievement in Mentoring Award. This award celebrates the commitment of the outstanding mentors in our community who promote the success of new investigators in the pursuit of independent orthopaedic research careers. It recognizes ORS members who have shown exceptional achievement in mentorship and advocacy on behalf of new investigators in orthopaedic research.
Students and faculty from UD’s Biomedical Engineering Society (BMES) visited the Johns Hopkins University (JHU) campus in Baltimore on Friday, March 27, to participate in the third annual BMES Undergraduate Research Day. Read more.
John Slater has been featured in the alumni profiles of the University of Texas, Austin where he received his PhD. There, he worked in Dr. Wolfgang Frey’s lab to develop nanopatterned surfaces to induce cancer-like behavior, increased proliferation and migration, in non-cancer cells. Read more.
BME grad student Rachel Edelstein received Honorable Mention in the 2015 NSF Graduate Research Fellowship Program (GRFP) competition for her proposed research on utilizing actively targeted nanoparticles coated with antibodies and small interfering RNA for the treatment of Triple Negative Breast Cancer, a form of breast cancer that is ineligible for many conventional treatments because it lacks the appropriate receptors.
Cole Galloway joined 75 other internationally recognized thought leaders at TEDMED 2014, “Unlocking Imagination in Service of Health and Medicine.” He shared the story of the GoBabyGo Program and focused on the importance of independent mobility for children to fully develop cognitively, emotionally and physically. Read more.
An interdisciplinary team of UD students and faculty have developed unique curriculum kits, called Orthopaedics in Action (OIA), that teach science, mathematics and engineering concepts through medical experiments. A team of BME seniors designed the first generation OIA curriculum. Read more.
BME undergrad Amira Idris has been selected as the Colonial Athletic Association Women’s Field Athlete of the Week. She won the long jump with a meet record and Eastern College Athletic Conference (ECAC) qualifying distance of 19 ft, 5.5 inches while also placing 4th in the 4 x 400 meter relay (48.66) and 9th in the 100 meters (12.54). Read more.
Jeannie Stephens is part of a team of UD faculty working to bring innovation and entrepreneurial education to students across disciplines thanks to UD’s selection for the National Science Foundation’s Pathways to Innovation Program. The objective is to rework the undergraduate programs to prepare students for the careers of tomorrow. Read more.
John Slater has received a 2-year INBRE Pilot Project award for his research on 3D microfluidic systems. His paper “Modulation of endothelial cell migration via manipulation of adhesion site growth using nanopatterned surfaces” has been accepted for publication in ACS Applied Materials & Interfaces.
Emily Day’s research group has published an invited perspective in ACS Nano that overviews nanoparticle-mediated photothermal therapy (PTT) and discusses recent insights into the mechanisms of cell death induced by this technique. PTT utilizes nanoparticles embedded within tumors to convert laser light energy into heat to ablate cancer cells. Depending on the laser irradiation conditions, PTT produces either necrosis or apoptosis, two distinct modes of cell death that impact therapy success differently. New information on the cellular signaling pathways involved in the PTT response provides researchers with a unique opportunity to enhance PTT’s successful elimination of cancer. Day recently received an ACCEL grant for breast cancer therapy using nanotechnology.
BME undergrad Amira Idris (on right) placed first in triple jump at the Eastern College Athletic Conference Championships (ECAC), becoming the first Blue Hen woman to capture an ECAC indoor title in a field event as she broke her own school record with a leap of 41-feet, 8-inches. Read more.
At the annual BMES conference in San Antonio, Texas in October 2014, UD’s BME program showed a strong presence. Our BME-affiliated faculty served as session chairs for 4 sessions. Moreover, 13 faculty and 3 graduate students presented 9 talks and 5 posters during the three day meeting, with topics covering biomaterials, drug delivery, orthopedic and rehabilitation engineering, tissue engineering and respiratory engineering. Read more.
At DBI’s Spin in Showcase, BME undergrad Gabriel Szczepanek (on right) presented with his team their innovation mTrigger. This device plugs into an iPhone’s headphone port and then attaches to sensor pads on a patient’s skin. As the patient goes through various exercises, the app records various parameters, tracking the patient’s progress. Read more.
The Delaware Rehabilitation Institute (DRI) at the University of Delaware is seeking four highly qualified undergraduate students for 10-week paid internships in summer 2015 in the areas of biomechanics and movement sciences. Read more
Hagit Shatkay and Chandra Kambhamettu in computer and information sciences have received a grant from the National Library of Medicine to apply to biomedical research the principle of “computational glancing.” Read more
Mark Mirotznik’s lab is working with the Army Research Office to engineer nanoplasmonic surfaces — materials structured at the atomic scale to interact with light in unusual and specific ways. Read more
Dean Ogunnaike named 2014 fellow of National Academy of Inventors, a high professional distinction accorded to academic inventors who have demonstrated a highly prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. Read more
BME congratulates Michela Taufer for being elected to the steering committee of the SC Conference Series, a premier international conference on high-performance computing, networking, storage and analysis that hosts more than 10,000 people each year. Read more
Emily Day is leading groundbreaking cancer research with UD students. Her team is currently creating second-generation spherical nucleic acids that have decreased brain tumors in animals and will soon be tested on breast cancer in human subjects. Read more
SimuTrach, a device developed by UD engineering students that provides realistic training for the care of tracheostomy patients, was selected as the first-place technology innovation winner by the 15th International Meeting on Simulation in Healthcare Scientific Content Committee. Read more
On October 3rd, a group of engineering students, including BME students, were invited to Air Liquide in Newark, Delaware for National Manufacturing Day with Senator Coons. They learned about the company and its life sciences department. Air Liquide plans to invest into expanding its medical and healthcare R&D in the next few years and is interested in biomedical engineers.
During summer 2014, a team of UD BME students were selected to attend the BMES Coulter College. The team included 6 BME juniors and was led by Dr. Anita Singh (Assistant Professor for Instruction in BME) and by a clinical collaborator, Michael McCulloch, from Nemours.
Coulter College is a training program supported by the Wallace H. Coulter Foundation that focuses on the translation of biomedical innovations. Topics include patent law, regulatory strategy, reimbursement codes, working with technology transfer offices, follow-on funding sources, and more. Student design teams are guided by faculty and clinical experts through a highly dynamic process that is designed to help them better understand how innovations can meet clinical needs, and that provides tools and approaches that are required to accelerate the translation of biomedical innovations to the market place to improve patient care.
- Millicent Sullivan collaborates to engineer bone repair
- Manning Triplets Graduate
- Abraham Lenhoff receives Francis Alison Award
- Terry Papoutsakis receives Delaware Bio Award
- BME Congratulates Ioannis Poulakakis on NSF Career Award!
- Thomas Epps and Millicent Sullivan publish paper in Nature Communications
- Three University of Delaware students named 2014 Goldwater Scholars
- BME clinical immersion course culminates with poster session.
- BME students and faculty participate in INBRE Summer Scholars program.
- John Rabolt named member of the National Academy of Inventors.
- BME undergrad receives Honors Enrichment Award to volunteer in Peru.
- Lucas Lu receives Rising Star Award.
- News Journal: Engineering students collaborate on exoskeleton to make moving easier for baby.
- BME students invited to present at Clinton Global Initiative.
- Xinqiao Jia’s team develops “smart” hydrogel.
- Cole Galloway receives NSF grant.
- Ryan Zurakowski co-authors Nature Medicine paper.
- Congratulations to the first BME graduates!
- Steven Stanhope and Cathy Wu appointed to lead Delaware INBRE.