Featured: check out our latest article with free access until April 9, 2024:

AL Lopez-Ruiz, ED Slaughter, AM Kloxin, CA Fromen, “Bridging the gender gap in autoimmunity with T-cell-targeted biomaterials,” Current Opinion in Biotechnology, 86, 103075, 2024. DOI: 10.1016/j.copbio.2024.103075

In review

  1. J Graf, K Bomb, M Trautmann-Rodriguez, BM Jarai, N Gill, AM Kloxin, CA Fromen, “Macrophage variance: investigating how macrophage origin influences responses to soluble and physical cues with immortalized vs. primary cells in 2D and 3D culture.”
  2. SE Cassel, B Huntington, W Chen, P Lei, S Andreadis, AM Kloxin, “Dynamic reporters for probing real-time activation of human fibroblasts from single cells to populations.”

Full list of our publications can be found at Google Scholar

  1. AL Lopez-Ruiz, ED Slaughter, AM Kloxin, CA Fromen, “Bridging the gender gap in autoimmunity with T-cell-targeted biomaterials,” Current Opinion in Biotechnology, 86, 103075, 2024. DOI: 10.1016/j.copbio.2024.103075
  2. LL Palmese, PJ LeValley, L Pradhan, AL Parsons, JS Oakey, M Abraham, SM D’Addio, AM Kloxin, Y Liang, KL Kiick, “Injectable liposome-containing click hydrogel microparticles for release of macromolecular cargos,” Soft Matter, 20, 1736-175, 2024. DOI: 10.1039/D3SM01009K
  3. J Graf, M Trautmann-Rodriguez, S Sabnis, AM Kloxin, CA Fromen, “On the path to predicting immune responses in the lung: Modeling the pulmonary innate immune system at the air-liquid interface (ALI),” European Journal of Pharmaceutical Sciences, 191, 106596, 2023. DOI: 10.1016/j.ejps.2023.106596
  4. PA Taylor, S Kroneberger, AM Kloxin, A Jayaraman, “Effects of solvent conditions on the self-assembly of heterotrimeric collagen-like peptide (CLP) triple helices: a coarse-grained simulation study,” Soft Matter, 12, 725-732, 2023. DOI: 10.1039/D3SM00374D
  5. K Bomb, Q Zhang, EM Ford, CA Fromen, AM Kloxin, “Systematic D-amino acid substitutions to control peptide and hydrogel degradation in cellular microenvironments, ACS Macro Letters, 12, 725-732, 2023. DOI: 10.1021/acsmacrolett.3c00144
  6. L Pradhan, DV Moore, EM Ovadia, SL Swedzinski, T Cossette, RA Sikes, K van Golen, AM Kloxin, “Dynamic bioinspired coculture model for probing ER+ breast cancer dormancy in the bone marrow niche,” Science Advances, 9 (10), eade3186, 2023. DOI: 10.1126/sciadv.ade3186
  7. KA Wodzanowski, MV Anonick, LA Genova, AM Kloxin, CL Grimes, “Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab,” CourseSource, 10, 2023. DOI: 10.24918/cs.2023.11
  8. K Bomb, PJ LeValley, IR Woodward, SE Cassel, BP Sutherland, A Bhattacharjee, Z Yun, J Steen, E Kurdzo, J McCoskey, D Burris, K Levine, C Carbrello, AM Lenhoff, CA Fromen, AM Kloxin, “Cell Therapy Biomanufacturing: Integrating Biomaterial and Flow‐Based Membrane Technologies for Production of Engineered T‐Cells,” Advanced Materials Technologies, 2201155, 2023. DOI: 10.1002/admt.202201155
  9. K Bomb, L Pradhan, Q Zhang, BM Jarai, A Bhattacharjee, D Burris, AM Kloxin, CA Fromen, “Destructive fibrotic teamwork: how both microenvironment stiffness and profibrotic interleukin 13 impair alveolar macrophage phenotype and function,” Biomaterials Science, 10, 5689-5706, 2022. DOI: 10.1039/d2bm00828a
  10. U Blache, EM Ford, B Ha, L Rijns, O Chaudhuri, PYW Dankers, AM Kloxin, JG Snedeker, E Gentleman, “Engineered hydrogels for mechanobiology,” Nature Reviews Methods Primers, 2, 98, 2022. DOI: 10.1038/s43586-022-00179-7
  11. PJ LeValley, AL Parsons, BP Sutherland, KL Kiick, JS Oakey, AM Kloxin, “Microgels Formed by Spontaneous Click Chemistries Utilizing Microfluidic Flow Focusing for Cargo Release in Response to Endogenous or Exogenous Stimuli,” Pharmaceutics, 14, 1062, 2022.
  12. PA Taylor, AM Kloxin, A Jayaraman, “Impact of collagen-like peptide (CLP) heterotrimeric triple helix design on helical thermal stability and hierarchical assembly: A coarse-grained molecular dynamics simulation study,” Soft Matter, 18, 3177-3192, 2022. DOI: 10.1039/D2SM00087C
  13. AP Liu, EA Appel, PD Ashby, BM Baker, E Franco, L Gu, K Haynes, NS Joshi, AM Kloxin, PHJ Kouwer, J Mittal, L Morsut, V Noireaux, S Parekh, R Schulman, SKY Tang, MT Valentine, SL Vega, W Weber, N Stephanopoulos, O Chaudhuri, “The ‘living interface’: a bridge between synthetic biology and biomaterials,” Nature Materials, 21, 390-397, 2022. DOI: 0.1038/s41563-022-01231-3
  14. KA Wodzanowski, JL Caplan, AM Kloxin, CL Grimes, “Multiscale Invasion Assay for Probing Macrophage Response to Gram-Negative Bacteria,” Frontiers in Chemistry, 10, 2022
  15. KL Wiley, BP Sutherland, BA Ogunnaike, AM Kloxin, “Rational design of hydrogel networks with dynamic mechanical properties to mimic matrix remodeling,” Advanced Healthcare Materials, 11, 2101947, 2021. DOI: 10.1002/adhm.202101947
  16. M Rabionet; E Polonio-Alcala; J Relat; M Yeste; J Sims-Mourtada; AM Kloxin; M Planas; L Feliu; J Ciurana; T Puig, “Fatty acid synthase as a feasible biomarker for triple negative breast cancer stem cell subpopulation cultured on electrospun scaffolds,” Materials Today Bio, 12, 100155, 2021. DOI: 10.1016/j.mtbio.2021.100155
  17. EM Ford, AM Kloxin, “Rapid production of multifunctional self-assembling peptides for incorporation and visualization within hydrogel biomaterials,” ACS Biomaterials Science & Engineering, 7, 4175-4195, 2021. DOI: 10.1021/acsbiomaterials.1c00589
  18. AM Hilderbrand, PA Taylor, F Stanzione, M Larue, C Guo, A Jayaraman, AM Kloxin, “Combining simulations and experiments for the molecular engineering of multifunctional collagen mimetic peptide-based materials,” Soft Matter, 17, 1985-1998, 2021. DOI:10.1039/d0sm01562h
  19. BM Jarai, Z Stillman, K Bomb, AM Kloxin, CA Fromen, “Biomaterials-Based Opportunities to Engineer the Pulmonary Host Immune Response in COVID-19,” ACS Biomaterials Science & Engineering, 7, 1742-1764, 2021. doi:10.1021/acsbiomaterials.0c01287
  20. T Sulerud, AB Sami, G Li, A Kloxin, J Oakey, J Gatlin, “Microtubule-dependent pushing forces contribute to long-distance aster movement and centration in Xenopus laevis egg extracts,” Molecular Biology of the Cell, 31, 2791–2802, 2020. DOI:10.1091/mbc.e20-01-0088
  21. RC Locke, EM Ford, KG Silbernagel, AM Kloxin, ML Killian, “Success criteria and preclinical testing of multifunctional hydrogels for tendon regeneration,” Tissue Engineering Part C: Methods, 26, 10, 506-518, 2020. DOI: 10.1089/ten.tec.2020.0199
  22. PJ LeValley, BO Sutherland, J Jaje, S Gibbs, M Jones, R Gala, CJ Kloxin, KL Kiick, AM Kloxin, “On-demand and tunable dual wavelength release of antibodies using light-responsive hydrogels,” ACS Applied Bio Materials,3, 10, 6944-6958, 2020. DOI: 10.1021/acsabm.0c00823
  23. BP Sutherland, PJ LeValley, DJ Bischoff, AM Kloxin, CJ Kloxin, “Sequence-defined vinyl sulfonamide click nucleic acids (VS-CNAs) and their assembly into dynamically responsive materials,” Chemical Communications, 56, 11263-11266, 2020. DOI: 10.1039/D0CC04235H
  24. EM Ovadia, L Pradhan, LA Sawicki, JE Cowart, RE Huber, SW Polson, C Chen, KL van Golen, KE Ross, CH Wu, AM Kloxin, “Understanding ER+ Breast Cancer Dormancy using Bioinspired Synthetic Matrices for Long-term 3D Culture and Insights into Late Recurrence,” Advanced Biosystems, 4, 9, 2000119, 2020. DOI: 10.1002/adbi.202000119
  25. SJ Ma, EM Ford, LA Sawicki, BP Sutherland, NI Halaszynski, BJ Carberry, NJ Wagner, AM Kloxin, CJ Kloxin,“Surface Chemical Functionalization of Wrinkled Thiol–Ene Elastomers for Promoting Cellular Alignment,”ACS Applied Bio Materials, 3, 6, 3731-3740, 2020. DOI: 10.1021/acsabm.0c00346
  26. KA Wodzanowski, SE Cassel, CL Grimes, AM Kloxin, “Tools for probing host-bacteria interactions in the gut microenvironment: from molecular to cellular levels,” Bioorganic & Medicinal Chemistry Letters, 30, 10, 127116, 2020
  27. PJ LeValley, R Neelarapu, BP Sutherland, S Dasgupta, CJ Kloxin, AM Kloxin, “Photolabile Linkers: Exploiting labile bond chemistry to control mode and rate of hydrogel degradation and protein release,” Journal of the American Chemical Society, 142, 10, 4671-4679, 2020. DOI: 10.1021/jacs.9b11564
  28. AM Hilderbrand, EM Ford, C Guo, JD Sloppy, AM Kloxin, “Hierarchically structured hydrogels utilizing multifunctional assembling peptides for 3D cell culture,” Biomaterials Science, 8, 1256-1269, 2020. DOI: 10.1039/C9BM01894H
  29. AI Marusina, AA Merleev, JI Luna,  L Olney,  NE Haigh,  D Yoon, C Guo,  EM Ovadia,  M Shimoda,  G Luxardi,  S Boddu,  NN Lal, Y Takada,  KS Lam,  R Liu,  RR Isseroff,  S Le,  JA Nolta, AM Kloxin^,  Emanual Maverakis^, “Tunable hydrogels for mesenchymal stem cell delivery: Integrin-induced transcriptome alterations and hydrogel optimization for human wound healing,” Stem Cells, 38, 231-245, 2020. DOI: 10.1002/stem.3105
  30. ME Smithmyer, SE Cassel, AM Kloxin, “Bridging 2D and 3D culture: Probing impact of extracellular environment on fibroblast activation in layered hydrogels,” AIChE J, 65, e16837, 2019. DOI:10.1002/aic.16837
  31. J Bisht, PJ LeValley, B Noren, R McBride, PM Kharkar, AM Kloxin, J Gatlin, and J Oakey, “Light-Inducible Activation of Cell Cycle Progression in Xenopus Egg Extracts Under Microfluidic Confinement,” Lab on a Chip, 19, 3499-3511, 2019. DOI: 10.1039/C9LC00569B
  32. KL Wiley, EM Ovadia, CJ Calo, RE Huber, AM Kloxin, “Rate-based approach for controlling the mechanical properties of ‘thiol-ene’ hydrogels formed with visible light,” Polymer Chemistry, 10, 4428-4440, 2019. DOI: 10.1039/C9PY00447E
  33. LA Sawicki, EM Ovadia, L Pradhan, JE Cowart, KE Ross, CH Wu, AM Kloxin, “Tunable synthetic extracellular matrices to investigate breast cancer response to biophysical and biochemical cues,” APL Bioengineering, 3, 016101, 2019. DOI: 10.1063/1.5064596
  34. PJ LeValley, AM Kloxin, “Chemical Approaches to Dynamically Modulate the Properties of Synthetic Matrices,” ACS Macro Letters, 8, 7-16, 2019. DOI: 10.1021/acsmacrolett.8b00808
  35. PJ LeValley, MW Tibbitt, B Noren, PM Kharkar, AM Kloxin, KS Anseth, M Toner, J Oakey “Immunofunctional photodegradable poly(ethylene glycol) hydrogel surfaces for the capture and release of rare cells,” Colloids and Surfaces B: Biointerfaces, 174, 483-492, 2019. DOI: 10.1016/j.colsurfb.2018.11.049
  36. H Wu, PJ LeValley, T, Luo, AM Kloxin, KL Kiick, “Manipulation of Glutathione-Mediated Degradation of Thiol-Maleimide Conjugates,” Bioconjugate Chemistry, 29, 3595-3605, 2018. DOI: 10.1021/acs.bioconjchem.8b00546
  37. ME Smithmyer, CC Deng, SE Cassel, PJ LeValley, BS Sumerlin, AM Kloxin, “Self-healing boronic acid-based hydrogels for 3D co-cultures,” ACS Macro Letters, 7, 1105-1110, 2018. DOI: 10.1021/acsmacrolett.8b00462
  38. ME Smithmyer, JB Spohn, AM Kloxin, “Probing fibroblast activation in response to extracellular matrix cues with well-defined culture platform,” ACS Biomaterials Science & Engineering, 4, 3304-3316, 2018. DOI: 10.1021/acsbiomaterials.8b00491
  39. PJ LeValley, B Noren, PM Kharkar, AM Kloxin, JC Gatlin, J Oakey, “Fabrication of Functional Biomaterial Microstructures by in Situ Photopolymerization and Photodegradation,” ACS Biomaterials Science & Engineering, 4, 3078-3087, 2018. DOI: 10.1021/acsbiomaterials.8b00350
  40. PJ LeValley, EO Ovadia, CA Bresette, LA Sawicki, E Maverakis, S Bai, AM Kloxin, “Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications,” Chemical Communications, 54, 6923-6926, 2018. DOI: 10.1039/C8CC03218A
  41. LJ Macdougall, KL Wiley, AM Kloxin, AP Dove, “Design of Synthetic Extracellular Matrices for Probing Breast Cancer Cell Growth Using Robust Cytocompatible Nucleophilic Thiol-yne Addition Chemistry,” Biomaterials, 178, 435-447, 2018. DOI: 10.1016/j.biomaterials.2018.04.046
  42. EO Ovadia, DW Colby, AM Kloxin, “Designing photopolymerized synthetic matrices for three-dimensional culture and differentiation of induced pluripotent stem cells,” Biomaterials Science, 6, 1358-1370, 2018. DOI: 10.1039/c8bm00099a
  43. NJ Smith, K Rohlfing, LA Sawicki, PM Kharkar, SJ Boyd, AM Kloxin, JM Fox, “Fast, Irreversible Modification of Cysteines through Strain Releasing Conjugate Additions of Cyclopropenyl Ketones,” Organic & Biomolecular Chemistry, 16, 2164-2169, 2018. DOI: 10.1039/C8OB00166A
  44. LA Sawicki, LH Choe, KL Wiley, KH Lee, AM Kloxin, “Isolation and identification of proteins secreted by cells cultured within synthetic hydrogel-based matrices,” ACS Biomaterials Science and Engineering, 4, 836-845, 2018. DOI: 10.1021/acsbiomaterials.7b00647
  45. MS Rehmann, KM Skeens, PM Kharkar, EM Ford, E Maverakis, KH Lee, AM Kloxin, “Tuning and predicting mesh size and protein release from step growth hydrogels,” Biomacromolecules, 18,3131-3142, 2017.DOI: 10.1021/acs.biomac.7b00781
  46. PM Kharkar, RA Scott, LP Olney, PF Levalley, E Maverakis, KL Kiick, AM Kloxin, “Controlling the release of small, bioactive proteins via dual mechanisms with therapeutic potential,” Advanced Healthcare Materials, 6, 1700713, 2017. DOI: 10.1002/adhm.201700713
  47. C Guo, H Kim, EM Ovadia, CM Mourafetis, M Yang, W Chen, AM Kloxin, “Bio-orthogonal conjugation and enzymatically triggered release of proteins within multi-layered hydrogels,” Acta Biomaterialia, 56, 80-90, 2017. DOI: 10.1016/j.actbio.2017.04.002
  48. LA Sawicki, AM Kloxin, “Light-mediated Formation and Patterning of Hydrogels for Cell Culture Applications,” Journal of Visual Experiments (115), e54462,2016. DOI: 10.3791/54462
  49. AM Hilderbrand, EM Ovadia, MS Rehmann, PM Kharkar, C Guo, AM Kloxin, “Biomaterials for 4D stem cell culture,” Current Opinion in Solid State Materials, 20, 212-224, 2016. DOI: 10.1016/j.cossms.2016.03.002
  50. MS Rehmann, JI Luna, E Maverakis, AM Kloxin, “Tuning microenvironment modulus and biochemical composition promotes human mesenchymal stem cell tenogenic differentiation,” Journal of Biomedical Materials Research Part A, 104, 1162–1174, 2016. DOI: 10.1002/jbm.a.35650
  51. PM Kharkar, MS Rehmann, KM Skeens, E Maverakis, AM Kloxin, “Thiol–ene click hydrogels for therapeutic delivery,” ACS Biomaterials Science and Engineering, 2, 165–179, 2016. DOI:10.1021/acsbiomaterials.5b00420
  52. PM Kharkar, KL Kiick, AM Kloxin, “Design of thiol- and light-sensitive degradable hydrogels using Michael-type addition reactions,” Polymer Chemistry, 6, 5565-5574, 2015. DOI:10.1039/C5PY00750J
  53. KA Tran, MY Cheng, A Mitra, H Ogawa, VY Shi, LP Olney, AM Kloxin, E Maverakis, “MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy,” Drug Design, Development and Therapy, 10, 43-52, 2015. DOI: 10.2147/DDDT.S93545
  54. E Maverakis, LA Cornelius, GM Bowen, T Phan, FB Patel, S Fitzmaurice, Y He, B Burrall, C Duong, AM Kloxin, H Sultani, R Wilken, SR Martinez, F Patel, “Metastatic Melanoma – A Review of Current and Future Treatment Options,” Acta Dermato-Venereologica, 95, 516-527, 2015. DOI: 10.2340/00015555-2035
  55. LA Sawicki, AM Kloxin, “Design of thiol–ene photoclick hydrogels using facile techniques for cell culture applications,” Biomaterials Science, 2, 1612-1626, 2014. DOI: 10.1039/c4bm00187g
  56. PM Kharkar, AM Kloxin, KL Kiick, “Dually degradable click hydrogels for controlled degradation and protein release,” Journal of Materials Chemistry B, 2, 5511-5521, 2014. DOI: 10.1039/C4TB00496E
  57. ME Smithmyer, LA Sawicki, AM Kloxin, “Hydrogel scaffolds as in vitro models to study fibroblast activation in wound healing and disease,” Biomaterials Science, 2, 634-650, 2014. DOI: 10.1039/C3BM60319A
  58. P Fischer [LeValley], M Tibbitt, A Kloxin, K Anseth, and J Oakey, “Photodegradable hydrogels for selective capture and release of mammalian cells,” Biomedical Sciences Instrumentation, 50, 62-67, 2014.
  59. MS Rehmann, AC Garibian, AM Kloxin, “Degradable thiol−ene hydrogels for protein release,” Macromolecular Symposia, 329, 58-65, 2013. DOI: 10.1002/masy.201200133
  60. PM Kharkar, KL Kiick, AM Kloxin,“Designing hydrogels for orthogonal control of degradable cell microenvironments,” Chemical Society Reviews, 42, 7335-7372, 2013. DOI: 10.1039/C3CS60040H
  61. MS Rehmann, AM Kloxin, “Tunable and dynamic soft materials for three-dimensional cell culture,” Soft Matter, 9, 6737-6746, 2013. DOI:10.1039/C3SM50217A
  62. DD McKinnon, AM Kloxin, KS Anseth, “Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons,” Biomaterials Science, 1, 460-469, 2013. DOI: 10.1039/C3BM00166K
  63. MW Tibbitt, AM Kloxin, LA Sawicki, KS Anseth, “Mechanical properties and degradation of chain and step polymerized photodegradable hydrogels,” Macromolecules, 46, 2785-2792, 2013. DOI: 10.1021/ma302522x
  64. MW Tibbitt, AM Kloxin, KS Anseth, “Modeling controlled photodegradation in optically thick hydrogels,” Journal of Polymer Science Part A: Polymer Chemistry, 9, 1899-1911, 2013. DOI: 10.1002/pola.26574
  65. AM Kloxin, KJR Lewis, CA DeForest, G Seedorf, MW Tibbitt, V Balasubramaniam, and KS Anseth, “Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D,” Integrative Biology, 4, 1540-1549, 2012. DOI: 10.1039/C2IB20212C
  66. H Wang, SM Haeger, AM Kloxin, LA Leinwand, KS Anseth, “Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus,” PLoS One, 7, e39969, 2012. DOI: 10.1371/journal.pone.0039969
  67. MW Tibbitt, BW Han, AM Kloxin, KS Anseth, “Synthesis and application of photodegradable microspheres for spatiotemporal control of protein delivery,” Journal of Biomedical Materials Research Part A, 100, 1647-1654, 2012. DOI: 10.1002/jbm.a.34107
  68. AM Kloxin, MW Tibbitt, and KS Anseth, “Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms,” Nature Protocols, 5, 1867-1887, 2010. DOI: 10.1038/nprot.2010.139
  69. MW Tibbitt, AM Kloxin, KU Dyamenahalli, and KS Anseth, “Controlled two-photon photoerosion of PEG hydrogels to study and manipulate subcellular interactions on soft materials,” Soft Matter, 6, 5100-5108, 2010. DOI: 10.1039/C0SM00174K
  70. AM Kloxin, CJ Kloxin, CN Bowman, and KS Anseth, “Mechanical properties of cellularly responsive hydrogels and their experimental determination,” Advanced Materials, 22, 3484-3494, 2010. DOI: 10.1002/adma.200904179
  71. AM Kloxin, MW Tibbitt, AM Kasko, JA Fairbairn, and KS Anseth, “Tunable hydrogels through controlled photodegradation for external manipulation of the cell microenvironment,” Advanced Materials, 22, 61-66, 2010. DOI: 10.1002/adma.200900917
  72. AM Kloxin, JA Benton, and KS Anseth, “In situ elasticity modulation with dynamic substrates to direct cell phenotype,” Biomaterials, 33, 1-8, 2010. DOI: 10.1016/j.biomaterials.2009.09.025
  73. AM Kloxin, AM Kasko, CN Salinas, and KS Anseth, “Photolabile hydrogels for dynamic tuning of physical and chemical properties,” Science, 324, 59-63, 2009. DOI: 10.1126/science.1169494
  74. VS Khire, AM Kloxin, CC Clouch, KS Anseth, and CN Bowman, “Synthesis, characterization and cleavage of linear polymers attached to silica nanoparticles formed using thiol-acrylate conjugate addition reactions,” Journal of Polymer Science A: Polymer Chemistry, 46, 6896-6906, 2008. DOI: 10.1002/pola.22999
  75. CR Nuttelman, AM Kloxin, and KS Anseth, “Temporal changes in PEG hydrogel structure influence human mesenchymal stem cell proliferation and matrix mineralization,” Advances in Experimental Medicine and Biology: Tissue Engineering, 585, 135-149, 2006. DOI: 10.1007/978-0-387-34133-0_10

Patents and patent applications

  1. “Light triggered wound mimicking system,” Patent Application US63/595,790, filed November 03, 2023.
  2. AM Kloxin, L Pradhan, R Sikes K van Golen, D Moore, “Indirect three-dimensional co-culture of dormant tumor cells and uses thereof,” Patent Application US17/764,593, US20220356452A1, filed September 30, 2020.
  3. KL Kiick, AM Kloxin, PM Kharkar, R Sivamani, E Maverakis, “Multimode degradable hydrogels for controlled release of cargo substances,” Patent US15/307,701, US20170258907A1, granted January 8, 2019.
  4. MW Tibbitt, KS Anseth, AM Kloxin, M Toner, J Oakey, A Shah, “Selective capture and release of rare cells using photodegradable hydrogels in a microfluidic platform,” Patent Application US14/905,460, US20160153999A1, granted March 1, 2022.
  5. KS Anseth, AM Kasko, MW Tibbitt, AM Kloxin, B Sridhar, “Photodegradable groups for tunable polymeric materials,” Patent US13/725,674, US9180196B2, granted November 10, 2015.