The nuclear magnetic resonance (NMR) Laboratory of the Department of Chemistry and Biochemistry houses six state-of-the-art NMR spectrometers with operating frequencies ranging from 400 MHz to 850 MHz. Our laboratory takes advantage of most recently enabling developments in NMR spectroscopy that have either expanded NMR applications or greatly improved the efficiency of the technique. The NMR laboratory provides NMR services, teaching, and user training to the University community. More than 25 research groups and more than 125 undergraduate students, graduate students, and postdoctoral researchers routinely use our services.
Two solution 400 MHz NMR spectrometers, one with an auto-sampler and a cryogenic QNP probe and another with the multinuclear capabilities, are available for routine proton and multinuclear NMR analysis of organic and inorganic materials. Two solution 600 MHz spectrometers, one with a triple-resonance cryogenic probe for biomolecular samples and another with an auto-sampler and enhanced 19F capabilities for expanded NMR applications such as high-resolution magic angle spinning (HRMAS) for semi-solid materials.
The 500 MHz solid-state NMR spectrometer is currently equipped with a 3.2 mm triple-resonance (1H, 13C, and 15N) probe for biosolids and other organic solid material. The 850 MHz spectrometer is hybridized for both solution and solid-state NMR measurements. With the ultra-high magnetic field and a large collection of solution and solid-state NMR probes, the 850 MHz NMR spectrometer covers a broad range of applications from inorganic material, synthetic organic polymeric materials to structure and dynamic studies in structural biology.
In addition to the departmental NMR instrument, four NMR spectrometers with frequencies ranging from 200 to 600 MHz are used and maintained by the following research group’s: Polenova, Dybowski, and Rozovsky. Most of these spectrometers are dedicated solid-state NMR instruments.