Corey, Jennie, Jianyu, and Jake’s cross coupling of alkyl amines is featured on Design for Science. Read it here: http://d4sci.com/activating-carbon-nitrogen-bonds-alkyl-amines-as-alkylating-agents/
Derek Lowe highlights our recent work in his blog, “In the Pipeline.” Read it here: http://blogs.sciencemag.org/pipeline/archives/2017/04/07/couple-your-primary-amines.
Congratulations to Corey Basch, Jennie Liao, Jianyu Xu, and Jake Piane for their recent discovery of a new nickel-catalyzed cross coupling of alkyl pyridinium salts (http://pubs.acs.org/doi/abs/10.1021/jacs.7b02389)! When coupled with efficient formation of pyridinium salts from primary amines, this reaction enables the use of alkyl amines to alkyl arenes. It is the first cross coupling of an alkyl amine derivative with unactivated alkyl groups.
Congratulations to Dr. Kelsey Cobb on the successful defense of your thesis! Kelsey’s research focused on new nickel-catalyzed cross couplings of amine and alcohol derivatives to prepare highly enantioenriched products. We wish you all the best in your next position at Solenis!
Welcome to our new website! Stay tuned for frequent updates on our research and group.
Congratulations to Dr. Jixin Liu on the successful defense of your thesis! In our group, Jixin pioneered the development of diastereoselective and enantioselective alkynylations of oxocarbenium and iminium ion intermediates. We wish you all the best in your next position at Adesis!