UD’s new NIH Center for Biomedical Research Excellence (COBRE) in Cardiovascular Health is pleased to announce a call for COBRE pilot research grants to expand and enhance the scientific goal of the center, which is to catalyze cardiovascular health research at UD. The COBRE pilot projects will provide funding for a one-year period that will allow investigators to develop more substantial external NIH support from individual or multi-investigator proposals.
We anticipate funding 2-3 projects this year. Projects will be awarded for 1 year, with a budget of $50,000 in direct costs.
DELAWARE PUBLIC MEDIA — As women age, their risk for cardiovascular disease becomes higher than men. According to Goredforwomen.org, it kills one in three women each year and affects over 44 million women in the United States. University of Delaware Physiologist Megan Wenner wants to understand the role changes in estrogen play in leading to this higher risk of heart disease. Read more >>
Hormones are the chemical envoys for our bodies. They communicate with our brains, heart, bones, muscles and, yes, reproductive organs. University of Delaware physiologist Megan Wenner is working to understand how sex hormones influence vascular function. She’s focused specifically on comparing estrogen effects in young and postmenopausal women. What happens after menopause when hormone levels drop dramatically? Are therapy interventions safe or not? Read more >>
Cardiovascular disease remains the number one cause of death for both men and women across the United States. The state of Delaware is in the bottom half of states for coronary heart disease death rates.
To help tackle this problem, the National Institute of General Medical Sciences at the National Institutes of Health has awarded the University of Delaware a five-year, $11.6 million grant to support a Center of Biomedical Research Excellence (COBRE) in cardiovascular health.
Dave Edwards, associate professor in the Department of Kinesiology and Applied Physiology, is the principal investigator. Read more >>
Researchers at the University of Delaware have published an article in the Feb. 4 issue of the Journal of Biological Chemistry, reporting on their work with a protein that can contribute to thrombosis, or dangerous clots inside blood vessels. Read more >>
Rhonda Prisby is conducting research on bone biology.
Bone marrow, the spongy tissue inside long bones, produces new blood cells and helps the lymphatic system work properly. But it may also turn out to be a progressively hostile microenvironment that induces vascular dysfunction and ossification, or hardening, of blood vessels. Read more >>
Megan Wenner and William Farquhar
Evidence is mounting for the connection between a sedentary lifestyle and chronic diseases like diabetes, cancer and cardiovascular disease. Read more >>
William Farquhar (left) and David Edwards of UD.
Sodium is essential for fluid balance and cellular homeostasis, or maintenance of a stable internal environment in an organism. But the amount of salt needed to maintain homeostasis in adults is quite low — about 500 milligrams (mg) per day. Read more >>