The Cardiovascular Research Core has the capability to provide the following services to COBRE investigators and others:

• Brachial artery flow mediated (FMD) with and without nitroglycerin
• Assessment of microvascular function via laser Doppler of cutaneous circulation
• Carotid artery intima-media thickness (IMT) measurements
• Standard and Doppler Carotid ultrasound
• Measures of arterial stiffness and wave reflection (pulse wave velocity (PWV), augmentation index
• Arterial waveform analysis (PWA)
• Central aortic pressure
• Cardiac echocardiography
• Heart rate variability
• Exercise testing in collaboration with the UD Nurse Managed Health Center
• Custom Vascular Studies: CVRC will be well equipped to handle customized studies with existing equipment or with investigator’s equipment.
• Cell culture facilities
• Biostatistical support

Personnel support will include ultrasound expertise, cell culture support, a research nurse, and support for graded exercise testing.