Publications

 
slide1 C Guo*, H Kim*, EM Ovadia*, CM Mourafetis, M Yang, W Chen, AM Kloxin, “Bio-orthogonal conjugation and enzymatically triggered release of proteins within multi-layered hydrogels,” Acta Biomaterialia, 2017 DOI: 10.1016/j.actbio.2017.04.002
 

 

 

slide1AM Hilderbrand*, EM Ovadia*, MS Rehmann, PM Kharkar, C Guo, AM Kloxin, “Biomaterials for 4D Stem Cell Culture,” Current Opinion in Solid State and Materials Science, 2016 DOI: 10.1016/j.cossms.2016.03.002

 

 

 

 

 

 

Sawicki 2016LA Sawicki, AM Kloxin, “Light-mediated Formation and Patterning of Hydrogels for Cell Culture Applications,” Journal of Visualized Experiments, 2016, DOI: 10.3791/54462

 

 

 

 

 

MS Rehmann, JI Luna, E Maverakis, Rehmann 2016AM Kloxin, “Tuning microenvironment modulus and biochemical composition promotes human mesenchymal stem cell tenogenic differentiation,” Journal of Biomedical Materials Research Part A, 2016 DOI: 10.1002/jbm.a.35650

 

 

Kharkar 2016

PM Kharkar, MS Rehmann, KM Skeens, E Maverakis, AM Kloxin, “Thiol–ene Click Hydrogels for Therapeutic Delivery,” ACS Biomaterials Science and Engineering, 2016 DOI: 10.1021/acsbiomaterials.5b00420

 

 

Maverakis 2016

 

 

KA Tran, MY Cheng, A Mitra, H Ogawa, VY Shi, LP Olney, AM Kloxin, and E Maverakis, “MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy,” Drug Design, Development and Therapy, 2016 DOI: 10.2147/DDDT.S93545

 

 

 

 

 

Sawicki 2015

 

 

LA Sawicki, AM Kloxin, “Biomaterials: Controlling Properties Over Time to Mimic the Dynamic Extracellular Matrix,” Royal Society of Chemistry, 2015 ISBN: 978-1-84973-833-0

 

 

 

 

Kharkar 2015

 

PM Kharkar, KL Kiick, AM Kloxin, “Design of thiol- and light-sensitive degradable hydrogels using Michael-type addition reactions,” Polymer Chemistry, 2015 DOI: 10.1039/C5PY00750J

 

 

 

 

Maverakis 2015

 

E Maverakis, LA Cornelius, GM Bowen, T Phan, FB Patel, S Fitzmaurice, Y He, B Burrall, C Duong, AM Kloxin, H Sultani, R Wilken, SR Martinez, F Patel, “Metastatic Melanoma – A Review of Current and Future Treatment Options,” Acta Dermato-Venereologica, 2015 DOI: 10.2340/00015555-2035

 

 

 

 

 

 

LA Sawicki, AM Kloxin, “Design of thiol–ene photoclick hydrogels using facile techniques for cell culture applications,” Biomaterials Science, 2014 DOI: 10.1039/C4BM00187G

 

 

 

 

 

Kharkar J Mater Chem B 2014

PM Kharkar, AM Kloxin, KL Kiick, “Dually degradable click hydrogels for controlled degradation and protein release,” Journal of Materials Chemistry B, 2014 DOI: 10.1039/C4TB00496E

 

 

Smithmyer Biomaterials Science 2014

ME Smithmyer, LA Sawicki, AM Kloxin, “Hydrogel scaffolds as in vitro models to study fibroblast activation in wound healing and disease,” Biomaterials Science, 2014. DOI: 10.1039/C3BM60319A

 

 

 

 

Rehmann Macromolecular Symposia 2013

MS Rehmann, AC Garibian, AM Kloxin, “Hydrolytically Degradable Thiol–ene Hydrogels for Protein Release,” Macromolecular Symposia, 329, 58–65, 2013. DOI: 10.1002/masy.201200133

 

 

 

 

Kharkar Chem Soc Rev 2013

 

PM Kharkar, KL Kiick, AM Kloxin, “Designing degradable hydrogels for orthogonal control of cell microenvironments,” Chemical Society Reviews, 42, 7335-7372, 2013. DOI: 10.1039/C3CS60040H

 

Rehmann Soft Matter 2013

 

MS Rehmann, AM Kloxin, “Tunable and dynamic soft materials for three-dimensional cell culture,” Soft Matter, 9, 6737-6746, 2013.  DOI: 10.1039/C3SM50217A

 

 

 

 

Tibbitt Macromolecules 2013

 

MW Tibbitt, AM Kloxin, LA Sawicki, KS Anseth, “Mechanical Properties and Degradation of Chain and Step Polymerized Photodegradable Hydrogels,” Macromolecules, 46, 2785-2792, 2013. DOI:10.1021/ma302522x

 

McKinnon Biomaterials Science 2013

 

DD McKinnon, AM Kloxin, KS Anseth, “Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons,” Biomaterials Science, 1, 460-469, 2013.  DOI: 10.1039/C3BM00166K

 

 

 

Tibbitt J Poly Sci 2013

 

MW Tibbitt, AM Kloxin, KS Anseth, “Modeling Controlled Photodegradation in Optically Thick Hydrogels,” Journal of Polymer Science Part A: Polymer Chemistry, 51, 1899-1911, 2013. DOI: 10.1002/pola.26574

 

 

Kloxin Int Bio 2012

 

AM Kloxin, KJR Lewis, CA DeForest, MW Tibbitt, V Balasubramaniam, and KS Anseth, “Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D,” Integrative Biology, 4, 1540-1549, 2012. DOI:10.1039/C2IB20212C

 

 

Wang PLoS One 2012

 

H Wang, SM Haeger, AM Kloxin, LA Leinwand, KS Anseth, “Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus,” PLoS One, 7, e39969, 2012. DOI:10.1371/journal.pone.0039969

 

Tibbitt J Biomed Maters Res 2012

 

MW Tibbitt, BW Han, AM Kloxin, KS Anseth, “Synthesis and application of photodegradable microspheres for spatiotemporal control of protein delivery,” Journal of Biomedical Materials Research Part A, 100, 1647-1654, 2012. DOI: 10.1002/jbm.a.34107

 

 

 

 

Kloxin Nat Protoc 2010

 

AM Kloxin, MW Tibbitt, and KS Anseth, “Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms,” Nature Protocols, 5, 1867-1887, 2010. DOI: 10.1038/nprot.2010.139

 

 

 

 

Tibbitt Soft Matter 2010

 

MW Tibbitt, AM Kloxin, KU Dyamenahalli, and KS Anseth, “Controlled two-photon photoerosion of PEG hydrogels to study and manipulate subcellular interactions on soft materials,” Soft Matter, 6, 5100-5108, 2010. DOI: 10.1039/C0SM00174K

 

 

Kloxin Adv Mater 2010 1

 

AM Kloxin, CJ Kloxin, CN Bowman, and KS Anseth, “Mechanical properties of cellularly responsive hydrogels and their experimental determination,” Advanced Materials, 22, 3484-3494, 2010. DOI: 10.1002/adma.200904179

 

 

 

 

Kloxin Adv Mater 2010 2

 

AM Kloxin, MW Tibbitt, AM Kasko, JA Fairbairn, and KS Anseth, “Tunable hydrogels through controlled photodegradation for external manipulation of the cell microenvironment,” Advanced Materials, 22, 61-66, 2010. DOI: 10.1002/adma.200900917

 

 

 

Kloxin Biomaters 2009

 

AM Kloxin, JA Benton, and KS Anseth, “Photodegradable hydrogels as dynamic substrates for probing the influence of elasticity on cell phenotypes,” Biomaterials, 31, 1-8, 2010. DOI:10.1016/j.biomaterials.2009.09.025

 

 

 

 

Kloxin Science 2009

 

AM Kloxin, AM Kasko, CN Salinas, and KS Anseth, “Photolabile hydrogels for dynamic tuning of physical and chemical properties,” Science, 324, 59-63, 2009. DOI: 10.1126/science.1169494

 

Khire 2008

 

VS Khire, AM Kloxin, CC Clouch, KS Anseth, and CN Bowman, “Synthesis, Characterization and Cleavage of linear polymers attached to Silica Nanoparticles formed using Thiol-acrylate Conjugate Addition Reactions,” Journal of Polymer Science A: Polymer Chemistry, 46, 6896-6906, 2008. DOI: 10.1002/pola.22999

 

 

AM Kloxin and KS Anseth, “Protein gels on the move,” Nature, 454, 705-706, 2008. [News & Views] DOI: 10.1038/454705a

CR Nuttelman, AM Kloxin, and KS Anseth, “Temporal changes in PEG hydrogel structure influence human mesenchymal stem cell proliferation and matrix mineralization,” Advances in Experimental Medicine and Biology: Tissue Engineering, 585, 135-149, 2006. DOI: 10.1007/978-0-387-34133-0_10